Pomegranate juice components block cancer cell migration

by S. L. Baker, features writer

(NaturalNews) One of the most dreaded consequences of cancer is when the disease metastasizes -- meaning it spreads from the primary site where it started to other parts of the body. But University of California, Riverside (UCR) scientists have announced what could be a major breakthrough in halting metastasis. They've discovered components in pomegranate juice that inhibit the movement of cancer cells and weaken the attraction of malignant cells to a chemical signal that has been shown to promote metastasis.

The UCR findings were just presented at the American Society for Cell Biology's 50th Annual Meeting, which is being held in Philadelphia. Specifically, the research team from the UCR laboratory of Manuela Martins-Green, Ph.D., found that pomegranate juice seems to block the spread of prostate cancer cells to the bone. The group is planning additional tests to determine the effects of various doses of the natural pomegranate compounds and whether there are any side effects.

In earlier studies, Dr. Martins-Green and her colleagues used a standardized concentration of pomegranate juice on two types of laboratory-cultured prostate cancer cells that were resistant to the male hormone testosterone. Scientists have long known that when cancerous cells are resistant to testosterone, that's an indicator those cells have a strong potential to metastasize. Not only did the research team find pomegranate juice killed many cancer tumor cells -- the pomegranate juice treatment also increased cell adhesion and decreased cell migration in those cancer cells that had not died.

Next the scientists analyzed the pomegranate juice to figure out which specific ingredients produced the molecular impact on cell adhesion and migration in metastatic prostate cancer cells. Dr. Martins-Green, graduate student Lei Wang and undergraduate student Jeffrey Ho discovered the answer: phenylpropanoids, hydrobenzoic acids, flavones and conjugated fatty acids found in the fruit.

"This is particularly exciting because we can now modify these naturally occurring components of the juice to improve their functions and make them more effective in preventing prostate cancer metastasis," Dr. Martins-Green said in a media statement."Because the genes and proteins involved in movement of prostate cancer cells are essentially the same as those involved in movement of other types of cancer cells, the same modified components of the juice could have a much broader impact in cancer treatment."

The idea that pomegranate phytochemicals have an anti-cancer effect isn't new. In fact, evidence has been steadily accumulating over the past few years that along with other health benefits (such as soothing inflammation in the body and potentially reducing the risk of heart disease) pomegranates can prevent and/or treat cancer. For example, earlier in 2010, NaturalNews reported on a study published in the journal Cancer Prevention Research showing that phytochemicals known as ellagitannins found in pomegranate fruit could prevent the development of hormone-dependent breast cancer and halt the growth of estrogen-driven tumors (https://www.naturalnews.com/027947_p...).

In addition, in a 2006 study of prostate cancer patients who drank eight ounces of pomegranate juice every day, UCLA researchers found a decline in prostate-specific antigen (PSA) levels that suggested a potential slowing of cancer progression. More recently, the results of a long-term study published in the Journal of Urology concluded pomegranate juice may effectively slow the progression of prostate cancer, even when regular treatment has failed (https://www.naturalnews.com/026190_c...).

However, despite all the science showing pomegranate juice could have anti-cancer effects, the Federal Trade Commission (FTC) has come down hard on claims about those potential benefits. In Sept. 2010, the FTC filed a lawsuit against Pom Wonderful, the natural foods company that provided the pomegranate juice for the UCLA research and has supported other research on pomegranate juice, charging the company's claims about the juice's health benefits were misleading.

More about the Pomegranate:

https://www.natmedtalk.com/wiki/Pomegranate

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"We can judge the heart of a man by his treatment of animals." ~Immanual Kant~

Pomegranate extract is alot more potent than the juice, considering the juice is mostly (98 or 99%) water.

One 500 mg capsule of extract = drinking approx one gallon of juice.

Now imagine taking cranberry extract, plum, apricot, raspberry, strawberry, orange, blueberry, mangosteen, goji, noni, elderberry, bilberry, cherry, camu camu, blackberry, apple, mango, acai, watermelon, grape seed, prune, beet, and hawthorn, two or three times per day.

That will repair damaged DNA and will protect you from every known disease, including cancers.

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Let Food Be Your Medicine And Medicine Be Your Food.(Hippocrates)

What is a good brand of pomegranite extract?

I bought a 16 oz bottle of Pomegranate Juice Concentrate, also a 16 oz Black Cherry Concentrate from
Vitacost for under $9.00 each. They make a great drink w/gin or votka too. Yuuuuum!

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May you always have..Love to Share, Health to Spare, and Friends that Care!

This is one of the supplements that I use personally:


https://gnhealthyliving.com/scripts/p...?idproduct=931

Ingredients:
Tomatoes 950 mg
Tart Cherry 950 mg
Apple Pectin 925 mg
Acerola 900 mg
Mangosteen 850 mg
Organic Flax seed 815 mg
Prune 800 mg
Maqui Berry 750 mg
Blood Oranges 725 mg
Red Wine Extract 650 mg
Pruen Rextract 625 mg
Plum 600 mg
Orange 600 mg
Pear 525 mg
Pomengranate 500 mg
Mangoes 500 mg
Watermelon 485 mg
Papaya 450 mg
Passion Fruit Extract 350 mg
Kiwi 250 mg
Green Tea Extract 250 mg
Bromelain 200 mg
Digestive Enzyme Blend 250 mg
Resveratrol 175 mg
Cinnamon 125 mg
Ginger root 50 mg
Probiotic Blend 8 billion CFU