I believe that even Dr. Simoncini has to get the bicarbonate as close to the cancer as possible for it to have an effect on the cancer. This is why his work involves intravenous injection. This is probably why MMS is believed to work better by IV. MMS is very alkaline. More so than bicarbonate. This may be why MMS could kill the Candida yeast; but it doesn't seem so successful with the Candida fungus. At least not in my experience. I believe kill reaction is due to the immediate shock rather than building an alkaline environment. A chemical or substance placed directly on cancer cells, especially in a petri dish, will be different from ingestion and maybe also injection. When someone swallows sodium bicarbonate, the first thing it contacts are the stomach acids. That will form sodium chloride (table salt) and carbon dioxide. Sodium chloride is considered acid forming, and carbon dioxide mixed with water forms carbonic acid. This is not a bad thing. I just think it confirms that a theory of alkaline environment has little to do with disease control. As I said before, it is understood that we need friendly flora; and one of their mechanisms is the production of acid which control unfriendly microbes. Candida yeast is a normal part of everyone's body. It is dimorphic. It can transform to fungus (the mycelium "hyphal" formation) and back to yeast (bud), when the environment is right for it.
In the following case, note that pH 4.5 is acid and conducive to bud formation; and 6.5 is alkali and conducive to mycelium state. Most fungus is not able to do this. Candida is.
Quote:
Stationary phase cultures of Candida albicans inoculated into fresh medium at 37 degrees C synchronously from buds at pH 4.5 and mycelia at pH 6.5. During bud formation, a filament ring forms just under the plasma membrane at the mother cell-bud junction at roughly the time of evagination. A filament ring also forms in mycelium-forming cells, but it appears later than in a budding cell and it is positioned along the elongating mycelium, on the average 2 microns from the mother cell-mycelium junction. Sections of filament rings in early and late budding cells and in mycelia appear similar. Each contains approximately 11 to 12 filaments equidistant from one another and closely associated with the plasma membrane. In both budding and mycelium-forming cells, the filament ring disappears when the primary septum grows inward. The close temporal and spatial association of the filament ring and the subsequent chitin-containing septum suggests a role for the filament ring in septum formation. In addition, a close temporal correlation is demonstrated between filament ring formation and the time at which cells become committed to bud formation at pH 4.5 and mycelium formation at pH 6.5. The temporal and spatial differences in filament ring formation between the two growth forms also suggest a simple model for the positioning of the filament ring.
https://www.biomedexperts.com/Abstrac...ndida_albicans
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The body will always strive to balance it's environment to only slightly alkaline, around 7.5.
Alkalizing has not been shown to cure cancer. After all, cesium chloride only shows a 50% success rate.