A Paleolithic diet is more satiating per calorie than a Mediterranean-like diet in individuals with ischemic heart diseaseThe full text is available at the link.

Bear in mind these were all portly men (waist size above 37inches - > 94 cm)
and they had heart disease + type 2 diabetes/impaired glucose tolerance so for them being able to lose weight on diet that wasn't calorie restricted (but that still reduced calorie intake 24%) was helpful.
Looking at the details at the end I think magnesium status should be corrected with supplements both before and during the trial as I doubt any were getting the amount of magnesium required to rebuild magnesium status.

It was a 12 week trial and when it comes to dietary change it does take a while for the current gut flora to change to best adapt to the new regime. I suspect that the next 12 weeks would have seen further improvements if the trial had continued longer. Also I'm not sure how strictly Paleo was interpreted. I'm all for people using coconut oil so I'm not sure if any oil was permitted or if they were cooking the lean meat in lard/dripping?

Ideally Paleo eating should be organic free range grassfed and not supermarket meat that's been fed grains. The grassfed, free range meat would be higher in omega 3 and low in omega 6 so less pro-inflammatory, but I doubt the trial would have afforded grassfed organic meat.

I'd also like to point out that true paleo's would be living near naked outdoor lives under unpolluted skies so would have higher VITAMIN D3 status. Probably in the region of 60~100ng/ml. Neither of these diets provided sufficient vitamin d and ideally both groups should have had 25(OH)D levels checked and raised above 40ng/ml 100nmol/l before the start of the trial as this optimizes insulin sensitivity.

Ted, what is the current recommendation for blood levels for D? and who makes those recommendations? I thought it was now 50... you mention 40 in your post.

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I'd like to suggest that the name Paleolithic diet be forgotten and replaced with the name Cave Man diet.
By the way, after a post on this diet by kind2creatures (thank you k2c) I went on it and a funny thing happened on my way to the forum. Originally i weighed 134 pounds (kg ?) and in no time at all while on the diet I weighed 125 lbs - and I was then eating like a horse.

It depends on who/what you read. I keep mine at 60ng/ml because that allows a good stored reserve of D3 in tissue.
But if we are expecting researchers to replete 25(OH)D status before a nutritional trial we would have to go for a level which at least is associated with maximum insulin sensitivity and so 40ng/ml would be the lowest acceptable level IMO.
The latest atrocious official recommendations seem to think that 20ng/ml would be acceptable but if your in the business of selling drugs or health care then obviously the lower the better, the more sick people there are the more profit you can make.

I went from 205/152 over six months. and am now able to eat what I want and drink more red wine than I should without regaining.
It is possible to regain the metabolic flexibility that allows you to remain at a constant weight without constantly monitoring every calorie that goes into your body or constantly worrying about the amount of exercise your doing.
It's the inflammatory nature of refined carbohydrates, sugars and HFCS, and the omega 6 seed oils that are the cause of the damage.

Ischemic heart disease is when the heart is not getting enough blood and oxygen because the arteries are blocked usually from plaque and cholesterol.

This study is beyond useless! It does not matter if it is true or not whether these people feel more satiated per calorie with a Paleo than a Mediterranean diet! The traditional Mediterranean diet, back when those populations consumed less meat is much more heart healthy. Meat after-all causes alot more cholesterol and plaque buildup.

I would be interested to see the evidence for that.

I'm sure we are aware that our brains use cholesterol to function. Surely only people who don't want fully functioning brains would want to lower their cholesterol levels. I'm sure we all know the many uses that vitamin d has in the body, and that vitamin d is made from the action of UVB on the cholesterol in the skin. Lower your cholesterol and you automatically lower your body's potential for creating vitamin d and consequently lower your immune function. There is a reason why people with higher cholesterol levels generally live longest.

Denise Minger explains why wheat consumption is a greater risk factor for heart disease than meat.

If you want to understand better how to reduce plaque then Dr Davis Heartscanblog is probably the best resource.

Denise Minger is a damn fool on a blog that went raw food vegan, refused to take any supplement like Vitamin B and was shocked that she got sick. Now she has a big head on her, plays the pretend expert that talks about her "bs-o-meter" going off from her laymen reading of the China Study. I don't need her advice.

The study you cited looked at a heavily diseased population and drew a conclusion from that. Not only that but the conclusion is totally useless, if you have Ischemic heart disease your concern should be improving and eliminating that condition, not how satiated you feel per calorie! Gary Null, whose health advice I follow(he also advises to eliminate wheat and I have long ago), complains that modern medicine is about sick care, symptomatology, when researchers do studies they prefer to study diseased population. They study diseased populations instead of healthy people whom we can learn alot more from. One of the few correct things sometimes done nowadays is promoting the traditional diet of the generally healthier Mediterranean people. The Paleo diet on the otherhand is a modern fad, constructed diet, promoted by specialists to create a captive market of adherents to sell their expertise in. Believe what you want. If you follow studies of sickly populations and think that those sickly people are examples to follow because they prove the Paleo diet is more satisfying per calorie, go ahead.

While I agree that vitamin b is missing from vegan diets I don't think you are being quite fair.
If you have any evidence to contradict her conclusions then it would be interesting to see that evidence.

Indeed but if you take that standpoint you would not bother to read any research as just about all human nutrition research is conducted in populations that are vitamin D, magnesium deficient and with omega 6 levels that are probably 20+ times higher than omega 3 status and therefore they are looking at people with low anti inflammatory resources and highly inflammatory bodies.
Whenever you read any research you have to keep your wits about you.

But surely losing weight is probably helpful for this condition and eating those foods that enable you to control your appetite better (and also those which also improve your lipid profile) makes life easier.

I will agree with that. The trouble is that even when they take a so called "healthy" control population they don't check them for Vitamin D omega 3 magnesium (or other common micronutrient) deficiencies so in practice are dealing with people probably in the early stages of metabolic syndrome.

Come on that's a bit rich. Are you really suggesting that paleo types haven't sufficient common sense to think for themselves?
I'm not at all sure the Med fans are on the right track either. You have to bear in mind that those eating a med style diet in the med region will have different vitamin d status to those people following the same diet in the UK or similar latitude. Compare herbs grown outside in the sun and in real soil in the Med with the same herbs grown in a polytunnel, in some soil-less medium. You won't persuade me that the herbs I buy in my supermarket have the same nutritional qualities as the same outdoor grown herbs freshly harvested bought in any Med market.

I only post information here I know to be true. I am certain that a low carbohydrate diet is more satiating than a Med style diet. It was changing from a med style to more paleo/low carb diet that enabled me to lose weight so perhaps I am biased but I do think saturated fat is a GOOD THING, and I suspect those foods that we evolved to consume rather than foods that we have introduced in the last 100 years are probably safe.
That rules out modern wheat varieties and I think we also have to be very suspicious of the nutritional content of modern supermarket fruit/veg varieties. Which is why I grow my own as much as possible and keep my own hens.

The Paleo diet is fake and constructed, period. Saying for our society to look at previous diets from the paleolithic era from which we have only poor reconstructions from archaeological/anthropological digs and fossile sites, to emulate what they ate thousands of years ago in a fake return to the past is a construct. Who is to determine what foods are "Paleo" or not. Also just because a previous society in a past stage of development did something, does not mean we should emulate them.

The hunter-gather societies that ate/eat meat often, had very, very tiny population densities compared to available game and natural habitat. Alot of these Price/Paleo followers like those present on this site say, "well we cannot all eat wild game, so ideally lets all eat grass fed meats as much as possible". We have high human population densities and not enough habitat to ever to achieve this. Not only that but it is not healthy compared to a largely plant and fruit based diet. People with chronic diseases like cancer, AIDs defining illnesses and diabetes have been cured with a vegan diet and lots of juicing. Let me know when the Paleo/Price people ever do similar.

That you lost weight personally, means nothing. People can lose weight doing unhealthy things like the Atkins diet as well, it does not mean it is worth emulating or elevating to a level that should command attention. Robert Atkins. himself accorded to Gary Null who knew and toured with him was an unhealthy person with unhealthy habits like drinking and smoking, yet he was and still is sadly, probably the most noted health guru in Western circles. The best way to lose weight is to eat high density, low calorie plants, especially greens. When you have lots of fat, it is a storage point for toxins, pesticides and other waste, so when you get rid of the fat, you body gets flooded with this refuse and you need something to chelate it out which greens will do.

Only to those who cannot think for themselves or apply a modicum of common sense.

While I accept that it will be impossible to reconstruct exactly the types of foods and lifestyles our early ancestors would have experienced we can eliminate from our diets many modern foods that we can be certain our DNA did not evolve to deal with.

Any person with sufficient common sense to grasp the idea that modern plant breeding and animal husbandry is focussed more on yield and profit than health and wellbeing. It is still possible to buy meat/veg/fruit raised traditionally and/or produce your own.

Indeed there are many aspects of paleo life that would not be acceptable today though it's also the case that many of the (by modern standards) reprehensible actions we see in war scenarios (rape of occupied populations) have their roots in DNA.

Perhaps you should read The Vegetarian Myth: Food, Justice and Sustainability Well that gave me a good laugh. I really don't think that argument is sustainable.

Cancer as a metabolic disease If you are going to beat cancer then you must stop enabling cancer cell proliferation. While I'm all for people maintaining a high vitamin c and antioxidant status and increasing magnesium status will all impact on cancer incidence and progression I think excess fructose consumption is probably more likely to speed cancer than slow it.
Please watch
Sugar: The Bitter Truth

Indeed but when we look at the most recent research we find improved markers of good health in those who follow these ideas.
The Battle of the Diets: Is Anyone Winning (At Losing?)

There are many people who say the opposite. Eventually the truth will out and common sense will triumph. But in the meanwhile I'll keep eating in a modified Atkins manner and I hope others will see how much healthier I am now than when I ate those foods promoted by health professionals, a low fat high carbohydrate diet.

I think this may be a problem and possibly explain why many people initially feel worse when starting to eat a low carbohydrate diet.
I think these problems can be avoided by increasing Coconut oil (MCT oil) consumption prior to reducing refined carbohydrate intake so the body is used to using ketone burning. I think we should also think more about the selenium status as well as vitamin D and magnesium when considering how best to deal with potential toxins in the body.

But I think we are going to have to agree to disagree on many topics.

My Mom's side of the family is from an island in greece called Icaria. It is one of the blue zones. Most of the population there are long lived and they smoke (heavily). What some scientists think is that it is due to the amount of veggies they eat combined with olive oil. (They also eat fish, meat, bread, lentils, wine)

<If you follow studies of sickly populations and think that those sickly people are examples to follow because they prove the Paleo diet is more satisfying per calorie, go ahead.>

2 things: Some of these people on extreme diets look like hippy scum that should be taken out by the national guard (IMO).

Also, deaths by ischemic heart disease have shown thatmany of these people are highly deficient in magnesium. There is some type of heart attack that occurs in highly magnesium deficient individuals which involves corornary arteries going into a spasm.

Indeed whatever "DIET" you follow there is the chance of micronutrient deficiency But we should recognise that most US/UK adults will NOT be meeting the current RDA for magnesium dieting or not dieting, and IMO the RDA for magensium is far too low.
We need to recognise that the less time fruit/veggies spend in the soil the lower their vitamin/mineral content there is not much point in growing/eating faster maturing higher yielding fruit and veg varieties if they are tasteless and are less nutrient dense.

Some of the best wines are grown at the highest altitude, More UVB more nutrients more flavour. Grow a faster maturing, higher yielding, grape in a soilless medium in a polytunnel and you would not expect the same flavour, nutrient density or health benefits.

About 8 yrs ago I was at a local pub owned by a former schoolmate. She made these canned hot peppers and gave me one. I was amazed how good it tasted and I asked her where she bought her peppers. She said she grew them and gave me a few raw ones. Fantastic (They were hungarian hots; Ted, you might know them as greek or italian peppers). The next day I was at a market and they had a basket of them for 3 bucks. I bought the basket and went home and chowed down on one. It was hot, but there was absoulutely NO FLAVOR what so ever. TASTELESS!