Sharon,
these are some notes I took at Dr Shallenbergers Class on Ozone therapy. He's an MD, a homeopath, and an expert on anti aging and the oxaditve therapies.
https://www.antiagingmedicine.com/
When you have an adrenal insufficiency you have a cortisol insufficiency.
A 24 hour urine collection is required for this test and special supplies may be required from the Lab.
Cortisol levels should be between 8 - 10
If it is decided that cortisol treatment is required always check the ACTH after a while. ACTH should not change.
If free T4 is low give iodine.
If free T4 is elevated do not give iodine.
Always treat adreanals first before treating thryroid as thryoid may change with cortisol treatment.
Dr Shallenberger would likely also say that there is an issue with toxicity and the krebs cycle may need a boost, especially if there is an issue with excess body fat. Ozone therapy will boost the krebs cycle and EWOT also. To boost the krebs you have to make sure that all necessarly nutrients are available, the glucose is low and oxygen is high.
Just breathing may not be good enough for those who a have lived a stressed and slouched lifestyle. Exercise is good, breathing exercises also.
Yogic breathing exercises as found in Kundaline yoga are excellent.
I don't know all that he would recommend but he has many of his patients on niacin to support krebs cycle function along with an oxygen therapy. Ozone therapy to attack any specific disease and detoxify, EWOT to generally hyperoxygenate the system.
He says that excess carbs in the diet distroy oxidation process in the cell. Fats should be running the cellular metabolism not glucose that is derived either from eating sugar or carbs.
L-Carnitine and R-Lipoic acid will help support and increase mitocondrial function in the krebs cycle.
Now there may be a way to reengergize the adrenals without taking cortisol I don't know. I would look at glandular supplements. Guess it just depends on how burnt out it is. Perhaps glandulars should be tried first and then if the desired effect is not attained then cortisol tried. Burnt out adrenals is not to be ignored.
I think that term is often used loosely. Stressed adrenals is probably better. A gland that is truly burned out can not be regenerated in which case cortisol is definately indicated.