Methylene Blue, a 100+ year old drug may be able to slow the progression or even cure Alzheimer's and Parkinson's disease.


https://www.sciencedaily.com/releases...0818101335.htm


***Methylene Blue also seems to have some fairly strong antimicrobial properties. And reportedly Methylene Blue is even effective against malaria.


A discussion about the use of Methylene Blue as an anti aging agent:

https://www.imminst.org/forum/index.p...pic=23947&st=0


Methylene Blue + Vitamin C for Parkinson's and Malaria:

https://www.earthclinic.com/CURES/parkinsons.html#MBVC

Very interesting find whetstone and thanks for bringing it here. I have read a little on methylene blue but did not find this!

anyone here dealing with Alzheimers want to try?

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Arrrowwind,

I just learned of this recently myself and yes it's extremely interesting!!

Methylene Blue is a 100+ year old, FDA approved drug and it's relatively cheap. Actually, you can buy Methylene Blue without a prescription and it is dirt cheap. For many years Methylene Blue has been used to treat/cure health conditions such as methemoglobinemia, cyanide poisoning, urinary tract infections, malaria etc..

Also, one of the things about Methylene Blue that has interested me is the fact that Methylene Blue kills pathogens such as fungi, viruses, bacteria protozoa etc.. And since I personally believe that pathogens cause or contribute to many chronic health problems I just can't help but wonder if Methylene Blue would be able to help those chronic health problems..???

From the above article:

"Used at a very low concentration � about the equivalent of a few raindrops in four Olympic-sized swimming pools of water."

Most interesting. This would be like a homeopathic dilution. So I went to my homeopathic remedy book and I did find Methylene Blue. Historically it has been used homeopathicaly in all potencies, in 3x potency. (this is how it is written in the book)

Here is a case from my book, although an allopahtic application not a homeopathic application:
A man, 50, suffered from cancer of the femur. Mosetig injected into the groin a a1 perent solution of "trichlorate of aniline" increasing the strength, until four grams were used at one injection. Almost an hour after the first injection the patient became dark blue, the next morning the discoloration was gone.

After the four-gram doses poisoning symptoms appeared unconsciousness, stertoruous breathing, feeble pulse, the whole body becoming dark blue. Artifical breathing and stimulants brought the patient around in four hours. Smaler doses ere used after that. In eight weeks he came home, cured to follow this ordinary work. Methyl-violet 1 to 500 and 1 to 1000 produced equally as good results (and I would guess without the crisis that followed the 4 gram injection)

The book goes on to say the homeopathic uses for:
In homeopathic potency Meth-b is a remedy for neuralgia, neurathenia, malaria, typhoid, here it diminishes the tympanites, delirium and fever, pus infection. Tendency to tremor, chorea, and eilepsy. Nephritis, (acute parenchymatous) scarlatinal nephritis. Urine acquires a green color. Bladder irritation from its use is antitoded by a little nutmeg. Used for surgical kidney with large amount of pus in urine. Gonorrheal rheumatism and cystitis. Bachace, sciatica, later states of stroke.

Cancerous ulcerations on the skin and mucous membranes and on internal organs such as uterus, lungs, and the gastrointestinal tract have been mitigated and cured by this remedy. the hemorrhages are mostly bright red with few clots, cough with blood-streaked expectorations and difficult breathing may be cure with Meth-b.

In a purely homeoapthic case:
The most homeopathic experiences is that of Halbert. Utilizing the affinity of Meth-b for nerve tissues and nerve cells, Halbert has given it in 3x tituraion with success in:
Neuralgias of neurathenia, tremor in neurasthenia, s pacticity of hysterical contraction, trophic disturbances, the resutl of nerve-exhaustion, spiral irritation.

Halbert confirms its anti-malarial powers and commends it in typhoid as an intestinal anti-septic. An apparently hopeless case of typhoid was signally benefited by it, the ty mpanites disappearing as if by magic. Wherever there is pus infection it is indicated and it has "made a record" with him in gonorrhea and cystitis.

So you can clearly see an affinity for this drugs action on nerve tissue, which of course is the site of Alzheimers disease. Pretty impressive on the infection front also. I wonder what dilution a few raindrops in 4 olympic pools would pan out to be in a homeopathic dilution? any homeopaths here want to venture a guess?

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Gosh! I'd hate to try to mix this myself. I'd have to make sure my Will is prepared.

Is there an already prepared homeopathic formula for this?

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- Jim

Arrowwind,

I believe the homeopathic dosage used in that study was 60mcg of Methylene Blue taken three times per day. So, that would be a total of 180mcg of Methylene Blue taken per day.

mcg = micrograms

This 180mcg per day dosage of Methylene Blue is a MUCH lower dosage than what a medical doctor would normally prescribe. So, I would have to think that the taking of a 180mcg of Methylene Blue per day would probably be a very safe dosage for most people.

Some people are buying "Kordon's Fish Medicine" (a 2.303% Methylene Blue solution) at fish and aquarium supply stores and then they are diluting that down until they get 60mcg of Methylene Blue per drop.


A pharmacist gave step by step instructions on how to dilute Kordon's Fish Medicine (a 2.303% Methylene Blue solution) down to the proper amount, in one drop from a medicine dropper.(It's at the very bottom of that page.)


https://groups.google.ms/group/sci.li...178fcaaf4eed25


Although, since Methylene Blue is an FDA approved drug for use in humans, a person could possibly have a 60 mcg dose of Methylene Blue compounded for them by a compounding pharmacy. Of course a medical doctor would have to write a prescription for this though.

Arrowwind,

I also found it interesting that your Homeopathic book mentioned combining Methylene Blue with Violet (I am assuming they meant Crystal Violet.)

I say that because according to the University of California the combination of Methylene Blue and Crystal Violet is very effective at killing pathogens in blood. Pathogens such as parasites,viruses, bacteria etc..


Methylene Blue and Crystal Violet helps the body fend off deadly
parasites:


https://www.universityofcalifornia.edu/news/article/4841

I am familiar with Gentian Violet, don't know if that is the same thing. They did not combine the two. The violet followed.

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Mcg, anything mcg really isn't a homeopathic dosage. Now the article states that a few drops in the equalivalent of 4 olympic size pools, that is more like a homeopathic dosage. Really hard to compare things with that kind of imagery. But a few drops in 4 olympic pools is diluted way beyond Avagadro's number. No chemist could find it.

Microgram is not very small compared to a homeoapthic dilution. a microgram is 1 one thousandth of a gram. so one microgram might be a 1m remedy if it were put in a dilution, one part Methyl-b and 999 parts water and if it is succussed, it could possibly be a homeoapthic preparation. But then the dose would be one drop. 60 mcg, I don't know what that would be. Not as dilute as 1mcg yet not within the homeopathic formulation principles. So I would say that this is not homeopathic, it is allopathic.

According to the use of Methly-b in my homeopathic remedy guide it may be used as a "similar" If the disease being treated is similar to what the remedy is known to cure then it is a homeopathic application. But the remedy must go through a dilution process, not just to give in a gross form.

In the remedy guide they say a 3x has been used...so for example you would take 1 cc of methyl-b and 9 cc of dilutant, likley water in this case, succuss it, then take 1cc of that and mix it with 9 cc of dilutant, succuss it and then once again for the 3rd time, take one cc of that and mix it with 9 cc of dilutant, succuss it and there you have your remedy in 3x potency. A dose would be one drop.

So you see there is quite a bit of difference in homepathic remedies and allopathic. I would say all in all this mcg gram thing is an allopathic administration. The primary law that has to be followed is the law of similars which in some cases may very well be even if given in a gross form.

An example of this would be chamomile tea. a cup of this tea given to a stressed out mom at the end of the day is a "similar" application and follows the homeopathic principle of "similars" and it may alleviate or palliate but because it may not be very "similar" repeated applications may be needed over days weeks, or forever because the mom keeps getting stressed out. Yet a homeopathic preparation may very well cure her forever in just one or two doses if her disease picture is similar enough.

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Apparently this stuff can be used to treat ALS also.

https://tinyurl.com/kpana6

Dan

And in that study you present, Dan, is a drug called dimebon used with Methyl-b that is pretty interesting.

https://www.medivation.com/pipeline_dimebon.html
https://en.wikipedia.org/wiki/Dimebolin

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Dan, thanks for posting that article.

And I noticed that in that study Methylene Blue (MB) was also tried alone.

The study said that when Methylene Blue was used alone it reduced TDP-43 aggregates by 50%. And that when Dimebon was used alone it reduced TDP-43 aggregates by 45%. And the combined use of Methylene Blue and Dimebon resulted in a 80% reduction in TDP-43 aggregates.


Quote from that article:

"Following treatment with 0.05 muM MB or 5 muM dimebon, the number of TDP-43 aggregates was reduced by 50% and 45%, respectively.

The combined use of MB and dimebon resulted in a 80% reduction in the number."


So according to that study Methylene Blue was effective when used alone. But the combination of Methylene Blue and Dimebon was even more effective.