Experiments by Dr. J. Berg, of Stanford University support the work of Dr. L.P. Hager, University of Illinois (USA). Namely that the chlorite contained in our Stabilised Oxygen significantly improves the efficiency of the two enzymes, chloroperoxidase and peroxidase, as well as utilizing myeloperoxidas in the leukocytes. There are two interesting outcomes of chlorite utilisation by these enzymes. The first is that the immune system may be directly enhanced by the increased rate of oxidation of foreign material by the leukocytes. The second is an increased ability by all metabolically active cells to scavenge free radicals. According to a report by S. Harakeh Ph.D. of Stanford, the rate of removal of the superoxide radicals by superoxide dismutase (SOD) will be increased as the peroxide removal is enhanced by the chlorite CLO2 . The resultant increased efficiency of the removal of free radicals is interesting in light of the contemporary theories attributing the cause of disease debilitating aspects of aging and onset of cancer to excessive levels of free radicals. The source of free radicals may be environmental or metabolic. Toxic free radicals are harmful free electrons which researchers feel can join with other atoms thus producing mutations which are harmful to the body. Leading researchers also concur on the theory that toxic free radicals may be responsible for a vast range of human ailments.
The chlorite, a major constituent of Stabilised Oxygen, and one of its reaction products (Chlorine dioxide) are extremely effective viricides, bactericides, and fungicides. Chlorine dioxide has been shown to be extremely effective against pathogenic agents such as legionella and enteric viruses such as the poliovirus in our laboratory. Its effectiveness against other viruses has also been demonstrated.
In 1983 Dr. James D. Berg at the Department of Medical Microbiology, at Stanford University School of Medicine, completed several studies on Stabilised Oxygen. Dr. Berg is the holder of two doctorates in medical microbiology and environmental engineering. He had been asked to explore the reasons why Stabilised Oxygen is so successful in treating human and animal disease conditions and in maintaining good health. The scientific literature on other chlorine chemistry is extensive, but studies on the chlorine ion and its role in human biochemistry are limited. Nevertheless, Dr. Berg’s conclusions more than adequately support the existing literature.
The following passage is by Dr. James Berg Ph.D.
I shall summarize some potential mechanisms for Stabilised Oxygen as a therapeutic agent. The hypotheses that follow are based on my research with chlorine dioxide and stabilised Oxygen, the research that has been conducted in other laboratories, and the hundreds of testimonials that have been obtained describing the efficacy of Stabilised Oxygen in the treatment of a variety of disorders.The first hypotheses addresses the topical application for the treatment of burns, abrasions and allergic reactions. The other two hypotheses primarily describe potential mechanisms following the ingestion, or when applied topically for the treatment of bacterial and viral infections.When applied topically Stabilised Oxygen may act as an osmotic agent similar to the application of Epsom Salts . The concentration of salts in the S.O. even when applied in a 1% solution, is quite high. The ensuing osmotic gradient would be a sufficient driving force for the removal of toxins and allergenic substances from the skin. The same gradient may in a similar way promote healing by increasing the rate of transport of factors involved in healing in the case of abrasions and burns. The aforementioned mechanism may appear simple, nonetheless it may partially explain the promotion of healing and desensitization of burns and rashes that have been documented.Secondly, in either topical or internal use the Stabilised Oxygen can act as a non-specific biocide. The chlorine, a major constituent of Stabilised Oxygen and one of its reaction products, chlorine dioxide, are extremely effective viricides, bactericides and fungicides as demonstrated at our laboratory. At a physiological pH, the predominant chemical species will be chlorine ion. The chlorine is biocidal, yet less effective against pathogens than chlorine dioxide since it is a less powerful oxidant in the ionic form. At the pH of the stomach (pH 3-4) one can expect chlorine dioxide to be produced from the chlorides. This will be a transient phenomenon ultimately yielding chlorine ion again. This will be absorbed by the body, passed through the lower intestinal tract and excreted by the kidneys. If a substantial dose of S.O. has been taken one could hypothesize that the chlorine and chlorine dioxide would act against any pathogenic microorganisms in the body. This may explain the increase in the efficiency of the enzymes known as peroxidases which are a important component in the immune system since they are involved in the oxidation of foreign material such as viruses and toxins. Our experiments with Stabilised Oxygen were modeled after the work of Dr. Lowell P. Hager at the University of Illinois on chlorine and our results support his findings. That Stabilised Oxygen or the chlorine it contains significantly improves the efficiency of the two enzymes chloroperoxidase and peroxidase. The reactions of another model system utilizing myeloperoxidase and peroxidase in the leukocytes is shown to increase the activity of this enzyme.
Additionally, Dr. Anderson Peoples, Professor of Pharmacology, University of California wrote of the Stabilised Oxygen as follows: I have concluded that as a bactericide and or fungicide, it works primarily on the basis of oxidation, apparently able to supply stimulus to the organism’s own physiological response as well as offering oxidative capacity at a cellular level.
His report concludes with the following statement :
We consider the Stabilised Oxygen where utilised in vivo, combines with the natural body functions and immune responses to become an effective medication with virtually no toxicity or side effects.
MATERIALS AND METHODS
The procedure as used by Mr. Humble follows: A 28% stock solution of 80% (technical grade) sodium chlorite (NaClO2) is prepared. The remaining 20% is a mixture of the usual excipients necessary in the manufacture and stabilization of sodium chlorite (NaClO2) powder or flake. Such are mostly sodium chloride (NaCl) ~19% , sodium hydroxide (NaOH) <1% , and sodium chlorate (NaClO3) <1% . The actual sodium chlorite (NaClO2) present is therefore 22.4%. Using a medium caliber dropper (25 drops per cc), the usual administered dose per treatment is 6 to 15 drops. In terms of milligrams of sodium chlorite (NaClO2), this calculates out to 9mg per drop or 54mg to 135mg per treatment. Effectiveness is enhanced, if prior to administration the selected drops are premixed with 2.5 to 5 cc of table vinegar or lime juice or 5-10% citric acid and allowed to react for 3 minutes. The resultant solution is always mixed into a glass of water or apple juice and taken orally. The carboxylic acids neutralize the sodium hydroxide (NaOH) and at the same time convert a small portion of the chlorite (ClO2-) to its conjugate acid known as chlorous acid (HClO2) . Under such conditions the chlorous acid (HClO2) will oxidize other chlorite anions (ClO2-) and gradually produce chlorine dioxide (ClO2). Chlorine dioxide (ClO2) appears in solution as a yellow tint which smells exactly like elemental chlorine (Cl2) . The above described procedure can be repeated a few hours later if necessary. Considerably lower dosing should be applied in children or in emaciated individuals scaled down according to size or weight. The diluted solution can be taken without food to enhance effectiveness but this often causes nausea. Drinking extra water usually relieves this. Nausea is less likely to occur if food is present in the stomach. Starchy food is preferable to protein as protein quenches chlorine dioxide (ClO2) . Significant amounts of vitamin C (ascorbic acid) must not be present at any point in the mixtures or else this will quench the chlorine dioxide (ClO2) and render it ineffective. For the same reason antioxidant supplements should not be taken on the day of treatment. Other side effects reported are transient vomiting, diarrhea, headache, dizziness, lethargy or malaise.
I first learned of Jim Humble's remarkable discovery in the fall of 2006. That sodium chlorite (NaClO2) or chlorine dioxide (ClO2) could kill parasites in vivo seemed immediately reasonable to me at the onset. It is well known that many disease causing organisms are sensitive to oxidants. Various compounds classifiable as oxides of chlorine such as sodium hypochlorite (NaClO) and chlorine dioxide (ClO2) are already widely used as disinfectants. What is novel and exciting here is that Mr. Humble's technique seems: 1) easy to use, 2) rapidly acting, 3) successful, 4) apparently lacking in toxicity, and 5) affordable. If this treatment continues to prove effective, it could be used to help rid the world of one of the most devasting of all known plagues. Especially moving in me is the empathy I feel for anyone with a debilitating febrile illness. I cannot forget how horrible I feel whenever I have caught influenza. How much more miserable it must be to suffer like that again and again every 2 to 3 days as happens in malaria. Millions of people suffer this way year round. 1 to 3 million die from malaria every year mostly children. Thus motivated I sought to learn all I could about the chemistry of the oxides of chlorine. I wanted to understand their probable mechanisms of toxicity towards the causative agents of malaria (Plasmodium species). I wanted to check available literature pertaining to issues of safety or risk in human use.
OXIDANTS AS PHYSIOLOGIC AGENTS
Oxidants are atoms or molecules which take up electrons. Reductants are atoms or molecules which donate electrons to oxidants. I was already very familiar with most of the medicinally useful oxidants. I had taught at numerous seminars on their use and explained their mechanisms of action on the biochemical level. Examples are: hydrogen peroxide , zinc peroxide , various quinones (e.g. benzoquinone , rhodizonic acid) , various glyoxals (e.g. glyoxal , methyl glyoxal , ozone , ultraviolet light, hyperbaric oxygen , benzoyl peroxide , anodes, artemisinin , methylene blue , allicin , iodine and permanganate . Some work has been done using dilute solutions of sodium chlorite (NaClO2) internally to treat fungal infections, chronic fatigue, and cancer; however, little has been published in that regard.
Low dose oxidant exposure to living red blood cells induces an increase in 2,3-diphosphoglycerate levels inside these cells. This attaches to hemoglobin (Hb) in such a way that oxyhemoglobin (HbO2) more readily releases oxygen (O2) to the tissues throughout the body.
Hyperbaric oxygenation (oxygen under pressure):
is a powerful detoxifier against carbon monoxide;
is a powerful support for natural healing in burns, crush injuries, and ischemic strokes; and
is an effective aid to treat most bacterial infections.
Taken internally, intermittently and in low doses many oxidants have been found to be powerful immune stimulants. Sodium chlorite (NaClO2) acidified with lactic acid as in the product "WF10" has similarly been shown to modulate immune activation. Exposure of live blood to ultraviolet light also has immune enhancing effects. These treatments work through a natural physiologic trigger mechanism, which induces peripheral white blood cells to express and to release cytokines. These cytokines serve as a control system to down-regulate allergic reactions and as an alarm system to increase cellular attack against pathogens.
Activated cells of the immune system naturally produce strong oxidants as part of the inflammatory process at sites of infection or cancer to rid the body of these diseases. Examples are: superoxide (*OO-) , hydrogen peroxide (H2O2) , hydroxyl radical (HO*) , singlet oxygen (O=O) and ozone (O3) . Another is peroxynitrate (-OONO) the coupled product of superoxide (*OO-) and nitric oxide (*NO) radicals.
-OO* + *NO -> -OONO
Yet another is hypochlorous acid (HOCl) the conjugate acid of sodium hypochlorite (NaClO) . The immune system uses these oxidants to attack various parasites.
OXIDES OF CHLORINE AS DISINFECTANTS
All bacteria have been shown to be incabable of growing in any medium in which the oxidants (electron grabbers) out-number the reductants (electron donors). Therefore, oxidants are at least bacteriostatic and at most are bacteriocidal. Many oxidants have been proven useful as antibacterial disinfectants. Hypochlorites (ClO-) are commonly used as bleaching agents, as swimming pool sanitizers, and as disinfectants. At low concentrations chlorine dioxide (ClO2) has been shown to kill many types of bacteria, viruses and protozoa. Ozone (O3) or chlorine dioxide (ClO2) are often used to disinfect public water supplies or to sanitize and deodorize waste water. Sodium chlorite (NaClO2) or chlorine dioxide (ClO2) solutions are used in certain mouth washes to clear mouth odors and oral bacteria. Chlorine dioxide (ClO2) sanitizes food preparation facilities. Acidified sodium chlorite is FDA approved as a spray in the meat packing industry to sanitized meat. This can also be used to sanitize vegetables and other foods. Farmers use this to cleanse the udders of cows to prevent mastitis, or to rid eggs of pathogenic bacteria. Chlorine dioxide (ClO2) can be used to disinfect endoscopes. Oxidants such as iodine , various peroxides , permanganate and chlorine dioxide can be applied topically to the skin to treat infections caused by bacteria or fungi.
MALARIA IS OXIDANT SENSITIVE
From November 2006 through May of 2007 I spent hundreds of hours searching biochemical literature and medical literature pertaining to the biochemistry of Plasmodia. Four species are commonly pathogenic in humans namely: Plasmodium vivax, Plasmodium falciparum, Plasmodium ovale and Plasmodium malariae. What I found was an abundance of confirmation that, just like bacteria, Plasmodia are indeed quite sensitive to oxidants. Examples of oxidants toxic to Plasmodia include: artemisinin , artemether , t-butyl hydroperoxide , xanthone , various quinones (e.g. atovaquone , lapachol , beta-lapachone , menadione ) and methylene blue .
Like bacteria, fungi and tumor cells, the ability of Plasmodia to live and grow depends heavily on an internal abundance of reductants. This is especially true regarding thiol compounds also known as sulfhydryl compounds (RSH) . Thiols as a class behave as reductants (electron donors). As such they are especially sensitive to oxidants (electron grabbers).
Thiols (RSH) such as glutathione and other sulfur compounds are reactive with sodium chlorite (NaClO2) and with chlorine dioxide (ClO2) . These are the very agents present in Mr. Humble's solution. Possible products of oxidation of thiols (RSH) using various oxides of chlorine are: disulfides (RSSR) , disulfide monoxides (RSSOR) , sulfenic acids (RSOH) , sulfinic acids (RSO2H) and sulfonic acids (RSO3H) .
None of these can support the life processes of the parasite. Upon sufficient removal of the parasite's life sustaining thiols (RSH) by oxidation, the parasite rapidly dies. A list of thiols (RSH) upon which survival of Plasmodium species heavily depend includes: dihydrolipoic acid , coenzyme A and acyl carrier protein , glutathione , glutathione reductase, glutathione-S-transferase, peroxiredoxin, thioredoxin, glutaredoxin, plasmoredoxin, thioredoxin reductase, falcipain and ornithine decarboxylase.
HEME IS AN OXIDANT SENSITIZER
Of particular relevance to treating malaria is the fact that Plasmodial trophozoites living inside red blood cells must digest hemoglobin (Hb) as their preferred protein source. They accomplish this by ingesting hemoglobin (Hb) into an organelle known as the "acid food vacuole". Incidently, the high concentration of acid in this organelle could serve as an additional site of conversion of chlorite (ClO2-) to the more active chlorous acid (HClO2) or chlorine dioxide (ClO2) right inside the parasite. Furthermore, Plasmodia consume 50 to 100 times more glucose than noninfected red blood cells most of which is metabolized to lactic acid another known activator of chlorite (ClO2-).
Next falcipain a hemoglobin digesting enzyme hydrolyzes hemoglobin protein to release its nutritional amino acids. A necessary byproduct of this digestion is the release of 4 heme molecules from each hemoglobin molecule digested. Free heme (also known as ferriprotoporphyrin IX) is redox active and can react with ambient oxygen (O2) , an abundance of which is always present in red blood cells. This produces superoxide radical (*OO-) , hydrogen peroxide (H2O2) and other reactive oxidant toxic species (ROTS). These can rapidly poison the parasite internally. To protect themselves against this dangerous side-effect of eating blood protein, Plasmodia must maintain a high reductant capacity (an abundance of reduced thiols (RSH) and NADPH ) to quench these ROTS. This is their main mechanism of antioxidant defense.
Plasmodia must also rapidly and continuously eliminate heme , which is accomplished by two methods. Firstly, heme is polymerized producing hemozoin. Secondly, heme is metabolized in a detoxification process that requires reduced glutathione (GSH) . Therefore any method (especially exposure to oxidants) which limits the availability of reduced glutathione (GSH) will cause a toxic build up of heme and of ROTS inside the parasite cells. Sodium chlorite (NaClO2) and chlorine dioxide (ClO2) (the exact agents present in Mr. Humble's treatment) readily oxidize glutathione (GSH). Therefore, a rapid killing of Plasmodia upon taking acidified sodium chlorite orally should be expected.
OVERCOMING ANTIBIOTIC RESISTANCE WITH OXIDATION
Now the issue of resistance of Plasmodium species to commonly used antiprotozoal antibiotics must be addressed. Quinine , chloroquine , mefloquine , quinacrine , amodiaquine , primaquine and other quinoline-like antibiotics all work by blocking the heme detoxifying system inside the trophozoites. Many Plasmodial strains against which quinolines have repeatedly been used have found ways to adapt to these drugs and to acquire resistance. Research into the mechanisms of resistance has found that often resistance is accomplished by a meere upregulation of glutathione (GSH) production and utilization. Consequently oxidizing or otherwise depleting glutathione (GSH) inside the parasite usually restores sensitivity to the quinoline antibiotics. Therefore, protocols combining the use of oxidants with quinolines are under developement and already showing signs of success. In this context let us consider that no amount of intraplasmodial glutathione (GSH) could ever resist exposure to a suffient dose of chlorine dioxide (ClO2) . Note that each molecule of chlorine dioxide (ClO2) can disable 1 to 5 molecules of glutathione (GSH) depending on the reaction mechanism.
2(GSH) + 2(ClO2) --> 1(GSSG) + 2(H+) + 2(ClO2-)
10(GSH) + 2(ClO2) --> 5(GSSG) + 2(H+) + 2(Cl-) + 4(H2O)
Acidified sodium chlorite could provide a powerful new opportunity to improve or to restore sensitivity to quinolines by virtue of its oxidative power. However, quinolines contain secondary amino groups or tertiary amino groups which react with chlorine dioxide (ClO2) in such a way that both could destroy each other. Some possible strategies to resolve this incompatibility are suggested below.
Acidified sodium chlorite could be used as explained above only as a solo therapy.
Quinoline administration could be withheld until after the acidified sodium chorite has completed its action.
Patients already preloaded with a quinoline could stop this, wait a suitable period of time for this to wash out, then administer the acidified sodium chlorite.
The quinoline could remain in use and while the less active sodium chlorite is administered without acid. This should retain plenty of oxidant effectiveness without destroying any quinoline or wasting too much oxidant.
Switch from a quinoline to an endoperoxide (such as artemisinin) or to a quinone (such as atovaquone) before using acidified sodium chlorite, as these may be less sensitive toward destruction by chlorine dioxide.
Similar problems apply to methylene blue and many other drugs if they have an unoxidized sulfur atom, a phenol group , a secondary amine or a tertiary amine. Such are reactive with the chlorine dioxide (ClO2) component.
REDUCTANT RECOVERY SYSTEMS
Living things possess a recovery system to rescue oxidized sulfur compounds. It operates through donation of hydrogen atoms to these compounds and thereby restores their original condition as thiols (RSH) .
2 [H] + (RSSR) -> 2(RSH)
This system is known as the hexose monophophate shunt. A key player in this system is the enzyme glucose-6-phosphate- dehydrogenase (G6PDH). This enzyme is an essential part of a complex process that produces NADPH the main provider of reductants to the reductases (enzymes which convert oxidized sulfur compounds back into thiols (RSH) ). Patients with a genetic defect of G6PDH, known as glucose-6-phosphate-dehydrogenase deficiency disease, are especially sensitive to oxidants and to prooxidant drugs. However, this genetic disease has a benefit in that such individuals are naturally resistant to malaria. They can still catch malaria, but it is much less severe in them, since they permanently lack the enzyme necessary to assist the parasite in reactivating glutathione disulfide (GSSG) and other oxidized thiols. Chlorine dioxide (ClO2) has been shown to oxidize and denature G6PDH by reaction with the tyrosine and the tryptophan residues inside the enzyme. Furthermore, G6PDH is sensitive to inhibition by sodium chlorate (NaClO3) , another member of the chlorine oxide family of compounds. Sodium chlorate (NaClO3) is a trace ingredient present in Jim Humble's antimalarial solution. Some sodium chlorate (NaClO3) should also be produced in vivo by a slow reaction of chlorine dioxide (ClO2) with water under alkaline conditions.
2(ClO2) + 2(OH-) -> (ClO2-) + (ClO3-) + H2O
The Plasmodia may attempt to restore any thiols (RSH) lost to oxidation. However, this becomes more difficult as G6PDH is inhibited by chlorine dioxide (ClO2) or by chlorate (ClO3-) .
While most available literature refers to redox imbalances causing depletion of necessary thiols (RSH) . Other mechanisms of toxicity of the oxides of chlorine against Plasmodia should also be considered. Oxides of chlorine are generally rapidly reactive with ferrous iron (Fe++) converting it to ferric (Fe+++). This explains why in cases of overdosed exposures to oxides of chlorine such as sodium chlorite (NaClO2) there was a notable rise in methemoglobin levels. Methemoglobin is a metabolically inactive form of hemoglobin in which its ferrous iron (Fe++) cofactor has been oxidized to ferric (Fe+++). In living things including parasites iron is a necessary cofactor for many enzymes. Thus it is reasonable to expect that any damage to Plasmodia caused by oxides of chlorine is compounded by conversion of ferrous (Fe++) cofactors to ferric (Fe+++) or other alterations of iron compounds. Superoxide dismutase (SOD) inside Plasmodial cells also utilizes iron in its active center. Chlorine dioxide also oxidizes manganese (Mn++).
Other metabolites necessary for survival and growth in tumors, bacteria and parasites are the polyamines. Plasmodia quit growing and die, when polyamines are lacking, or when their functions are blocked. Polyamines are also sensitive to oxidation and can be eliminated by strong oxidants. When oxidized, polyamines are converted to aldehydes , which are deadly to parasites and to tumors. Chlorine dioxide (ClO2) is known to be especially reactive against secondary amines . This includes spermine and spermidine the two main biologically important polyamines.
Thus any procedure, which is successful to oxidize both thiols (RSH) and polyamines does quadruple damage to the pathogen:
oxidation of the thiol containing protein ornithine decarboxylase
inhibits polyamine synthesis;
oxidation of the thiol containing protein S-adenosyl-L-methionine decarboxylase
also inhibits polyamine synthesis;
oxidation of the secondary amines spermidine and spermine
depletes polyamine supplies;
the products of polyamine oxidation are toxic aldehydes .
Purines are essential to many life processes. These molecules have a double ring structure. The rings are heterocyclic being composed of both carbon and nitrogen. The secondary amino nitrogen atoms are vulnerable to reaction with chlorine dioxide (ClO2) . Examples of important biologic purines are xanthine , hypoxanthine , inosine , guanine and adenine . Guanine and adenine are essential components of DNA and RNA necessary for all genetic functions and for all protein syntheses. Adenine is an essential component of the cofactors NADH , NADPH , FAD and ATP , necessary for many metabolic functions including oxidation- reduction and energy metabolism. Any purines lost because of chlorine dioxide (ClO2) exposure can be readily replaced by host cells. Plasmodia and other apicomplexae are uniquely vulnerable to purine deficiency as they lack the enzymes necessary to produce purines for themselves. Instead these must be scavenged from host cells and imported across the plasma membranes of the parasite cells. Drugs are under development to inhibit purine utilization by Plasmodia and are already showing signs of success. Temporarily destroying some of the purines in the blood as should occur upon brief exposure to chlorine dioxide (ClO2) in vivo is probably an additional stress that Plasmodia cannot tolerate.
Chlorine dioxide (ClO2) is highly reactive with thiols (RSH) , phenols , secondary amines and tertiary amines . Therefore, proteins composed of amino acids which present these reactive groups are vulnerable to oxidation by this agent. Proteins which present thiol groups as residue(s) of the amino acid L-cysteine are discussed above under TARGETING THIOLS. L-tyrosine presents a phenol group and is therefore similarly vulnerable. L-tryptophan , L-histidine , L-proline and 4-hydroy-L-proline present secondary amino groups which are also especially reactive with chlorine dioxide (ClO2) .
A remaining concern is safety. So far, at least anecdotally, the dosages of chlorine oxides as administered orally per Jim Humble's protocol have produced no definite toxicity. Some have taken this as often as 1 to 3 times weekly and on the surface seem to suffer no ill effects. To be certain if this is safe more research is warranted for such long term or repeated use. The concern is that too much or too frequent administration of oxidants could excessively deplete the body's reductants and promote oxidative stress. One useful way to monitor this may be to periodically check methemoglobin levels in frequent users. Sodium chlorite (NaClO2) , as found in municipal water supplies after disinfection by chorine dioxide (ClO2) , has been studied and proven safe. Animal studies using much higher oral or topical doses have proven relatively safe. In a suicide attempt 10g of sodium chlorite (NaClO2) taken orally caused refractory methemoglobinemia and nearly fatal kidney failure. Inhalation or aerosol exposure to chlorine dioxide (ClO2) gas is highly irritating and generally not recommended. Special precautions must be employed in cases of glucose-6-phosphate-dehydrogenase deficiency disease, as these patients are especially sensitive to oxidants of all kinds. Nevertheless, oral acidified sodium chlorite solutions might even be found safe and effective in them, but probably will need to be administered at lower doses.
It is hoped that this overview will spark a flurry of interest, and stimulate more research into the use of acidified sodium chlorite in the treatment of malaria. The above appreciated observations need to be proven more rigorously and published. The biochemistry most likely involved suggests that other members of the phylum Apicomplexa should also be sensitive to this treatment. This phylum includes: Plasmodium, Babesia, Toxoplasma, Cryptosporidium, Eimeria, Theileria, Sarcocystis, Cyclospora, Isospora and Neospora. These pathogens are responsible for widespread diseases in humans, pets and cattle. Other thiol (RSH) dependent parasites should also be susceptible to acidified sodium chlorite. For example Trypanosoma and Leishmania extensively utilize and cannot survive without the cofactor known as trypanothione. Each molecule of trypanothione presents 2 sulfur atoms and 5 secondary amino groups all of which are vulnerable to oxidative destruction from chlorine dioxide (ClO2) .
Chlorine dioxide (ClO2) has been proven to be cidal to almost all known infectious agents in vitro using remarkably low concentrations. This includes parasites, fungi, bacteria and viruses. The experiences noted above imply that this compound is tolerable orally at effective concentrations. Therefore extensive research is warranted to determine if acidified sodium chlorite is effective in treating other infections. We may be on the verge of discovering the most potent and broad spectrum antimicrobial agent yet known.
YEA] 09/07/2008: Carl from Philadelphia, PA writes: "I have also had the same experience with MMS. I felt the tingling sensation but I got no actual outbreaks/sores. MMS works very well to destroy bacteria, fungus, parasites, viruses etc. The issue with MMS is that it is fighting the fight against Herpes alone, hence the tingling sensations. MMS cannot to its best ability fully destroy the Herpes virus when it is protected by it lipid coat (Fat coating). Monolaurin (coconut oil) is a supplement that dissolves away and destroys the lipid coating on the Herpes Virus, leaving it naked and exposed to our immune system. Monolaurin is not a drug, therefore, the Herpes Virus does build immunity to it like it does with Valtrex. Many people who use Valtrex claim it stops working for them after 2 years. The reason for this is because the Herpes virus builds an immunity to it, making the virus stronger, smarter and harder to kill. I would not be surprised if the drug companies introduced a new & stronger drug that claims to be much stronger than Valtrex.
By using Monolaurin, which dissolves Herpes's lipid coating and also using MMS, which oxidizes and kills the virus along with a healthy diet you will be able to stop all future outbreaks. But please keep in mind that you must eat well and clean your system out. Nobody can claim that there is a cure for Herpes, but I believe the cure for herpes is right in front of us. If everyone in the U.S. with HSV donated $2 (for example) we would have enough money to hire our own researchers, doctors or even help a comapny focusing on this cure see their passion to the end."
I just find out last week that i have oral herpes 1 and I was doing some research to learn more about it. I found MMS, is anyone that you know did a blood test to make sure that the virus is not in the body anymore?
I really wants to know if MMS will kill the virus and make it disappear forever.
I have had many oral herpes outbreaks in the past, which usually happen after much exposure to the sun. Since I started on MMS, I have not had a single outbreak, even with ample exposure to the sun. It's been 4 months, still clear.
No no. I meant de-stressed. like you aren't as stressed as you use to be.. guess that was a poor choice in words
Either way, I think having less outbreaks is sufficient enough in itself. Alongside this, you might want to look into Oil of Oreganol (P73 concentration), as it's said to actually kill the Herpes virus. You can put it on an outbreak directly to shorten it's duration tremendously, and rubbing it on the spine (mainly the tips, both top and bottom) for an extended amount of time kills it, being that's where herpes resides.
Well, you can have a blood test to check to see if the herpes simplex virus still exists in the blood, but you are right when you say that if you have no outbreaks - it really doesn't matter. I did hear about someone who was cured, and had a blood test to prove it - and the doc just said that the original tests must have been wrong. It is incredible how reluctant most doctors are to dispute what they were taught in medical school. It would be wonderful if it were completely gone as that means that you will never have another outbreak - even if you become sick and your immune system gets overwhelmed.