In a study involving 44 healthy premenopausal women, subjects consuming a high-fat/low-fiber diet were found to have significantly higher levels of urinary total estrogens, estriol-3-glucuronide, 2-hydroxyestradiol, 16alpha-hydroxyestrone, the ratio of 2-hydroxyestrone/4-hydroxyestrone, and catechol, as compared to subjects consuming a low-fat/high-fiber diet.
After adjusting for total fiber intake, total intake of fat was significantly associated with plasma levels of estrone, estradiol, urinary levels of 2-hydroxyestrone, 2-hydroxyestradiol, the ratio of 2-hydroxyestrone/4-hydroxyestrone, and total urinary estrogens. No significant difference between the groups was found for the ratio of 2-hydroxyestrone/16alpha-hydroxyestrone.
These results highlight the influence of dietary factors, specifically intake of fat, on levels of various sex hormones in premenopausal women.
are they saying that the fiber makes no difference? or are they saying they just didn't take that into account?
ST,
It does make a difference. Generally speaking, high-fiber consumers had lower levels of estrogen.
This isn't the first evidence I've seen supporting this assertion. In fact, adding fiber is often recommended to help manage conditions that are influenced by excess estrogen (estrogen dominance).
Quote:
In a study involving 44 healthy premenopausal women, subjects consuming a high-fat/low-fiber diet were found to have significantly higher levels of urinary total estrogens, estriol-3-glucuronide, 2-hydroxyestradiol, 16alpha-hydroxyestrone, the ratio of 2-hydroxyestrone/4-hydroxyestrone, and catechol, as compared to subjects consuming a low-fat/high-fiber diet.
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After adjusting for total fiber intake, total intake of fat was significantly associated with plasma levels of estrone, estradiol, urinary levels of 2-hydroxyestrone, 2-hydroxyestradiol, the ratio of 2-hydroxyestrone/4-hydroxyestrone, and total urinary estrogens.
it sounded like they were just looking at the fat.