01-31-2008, 08:12 PM
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Lecturer
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Join Date: Apr 2006
Location: Propecia, CA
Posts: 1,852
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Fructose May Increase Risk of Gout
Quote:
To look in more detail, the team carried out a 12-year study of 46,000 men aged 40 years and over with no history of gout, asking them regular questionnaires about their diet.
Over the period, 755 newly diagnosed cases of gout were reported. The risk of developing the condition was significantly increased with an intake level of five to six servings of sugary soft drink per week.
This link was independent of other risk factors for gout such as body mass index, age, high blood pressure and alcohol intake.
Diet soft drinks did not increase the risk of gout but fruit juice and fructose rich fruits (apples and oranges) were associated with a higher risk, the researchers said.
But this finding needs to be balanced against the benefit of fruit and vegetables in preventing other chronic disorders like heart disease and stroke.
Dr Hyon Choi, from the University of British Columbia, in Vancouver said dietary advice for gout had focused on restricting purine-rich foods, such as red meat and beer.
He said practitioners should advise patients with gout to reduce their fructose intake.
"I can think of some situations, for example in severe treatment failure gout, where reducing sweet fruits, such as oranges and apples could help," he added.
Dr Andrew Bamji, president of the British Society for Rheumatology, said anecdotally cases of gout appeared to be rising.
"When you think about it, it makes a lot of sense in that fructose inhibits the excretion of uric acid.
"I will certainly change my advice to patients and I suspect the number drinking fructose is quite large."
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https://news.bbc.co.uk/2/hi/health/7219473.stm
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