Go Back Natural Medicine Talk > Health > Bones & Joints

LinkBack Thread Tools Display Modes
� #1
Old 01-09-2011, 05:40 PM
kind2creatures's Avatar
Super Moderator
Join Date: Apr 2009
Location: USA
Posts: 2,757
Blog Entries: 18
kind2creatures will become famous soon enoughkind2creatures will become famous soon enough
Default Rheumatoid Arthritis and Thunder God Vine

Ancient Herb May Ease
Rheumatoid Arthritis

AUGUST 2009�Thunder god vine, an herb used for centuries in China, may help people with rheumatoid arthritis (RA). Unlike the more common osteoarthritis, RA is a highly inflammatory condition that occurs when the immune system mistakenly attacks joint tissues.

In a study published in the August 18 edition of Annals of Internal Medicine, 121 RA patients with at least six swollen joints took either a prescription anti-inflammatory or an extract from thunder god vine (Tripterygium wilfordii Hook F, TwHF). After 24 weeks, roughly 65% of the participants who took TwHF showed at least a 20% improvement in symptoms, compared with 33% of those taking the drug.

RA affects 1.3 million Americans; 70% of those affected are women. It generally starts in the small joints of the hands and wrists. In addition to joint pain and swelling, other symptoms include fatigue, weakness, flu-like complaints and muscle pain. (from energytimes.com)
"We can judge the heart of a man by his treatment of animals." ~Immanual Kant~

NatMedTalk and Beyond
Reply With Quote
� #2
Old 01-10-2011, 11:53 AM
jfh jfh is offline
Super Moderator
Join Date: Dec 2007
Location: Texas, USA
Posts: 2,312
Blog Entries: 16
jfh will become famous soon enoughjfh will become famous soon enough

Also a male contraceptive.

Tripterygium wilfordii , or lei gong teng, is a twining vine in the botanical family Celastraceae common to southern China . T. wilfordii and its botanical cousins T. hypoglaucum and T. regeli have been used in traditional Chinese medicine for over 2000 years, treating everything from fever and chills to edema and carbuncles. More recently it has been used to treat rheumatoid arthritis, chronic hepatitis, chronic nephritis, and several skin disorders.

Some men given T. wilfordii by their doctors are not able to conceive children. T. wilfordii�s contraceptive effect has been anecdotally known in China for many years; the first published finding came in 1982. A derivative of T. wilfordii could be an effective pharmaceutical alternative to contraceptives based on hormonal manipulation.
Most of the current studies on Tripterygium extracts take place in China , under the auspices of the Jiangsu Family Health Institute and Beijing and Shanghai �s Institute of Materia Medica. A group of researchers at Harbor-UCLA�s Medical Center has also investigated one of T. wilfordii�s derivatives, triptolide.
How does it work?

T. wilfordii has not been tested in men as a contraceptive. What we know about its contraceptive effects comes from studies on rodents and retrospective studies of men taking a Tripterygium preparation for some other medical reason. These studies show that low doses of various Tripterygium preparations produce significantly lowered sperm density, with the remaining sperm incapable of swimming effectively. One study suggests that, like nifedipine, T. wilfordii derivatives may act as calcium channel blockers (Bai 2002). Much current research is focused on establishing the mechanism by which the plant affects fertility and investigating potential toxicity and side effects.
How is it delivered?

In traditional Chinese medicine, men prescribed some form of Tripterygium would make a decoction by simmering peeled, dried roots of the plant for at least an hour. Depending on the malady being treated, a doctor would prescribe 15-25 grams of Tripterygium prepared in this way each day. Researchers have found that a decoction is an effective contraceptive at one-third of this dose, or 5-8 grams per day (Qian 1987).

Although the dried roots are commonly available in Chinese pharmacies around the world, Researchers do not expect that preparing a decoction everyday is a practical way to deliver a male contraceptive. They are investigating a number of different Tripterygium preparations as possible contraceptives. These preparations would most likely be delivered in the form of a tablet or pill.
What side effects are expected?

The doses of T. wilfordii root decoction used to treat arthritis or skin diseases can cause a host of side effects, including gastrointestinal distress and suppression of the immune system (Qian 1987). But a decoction is not under consideration as a male contraceptive; researchers are investigating half a dozen extracts of varying purity. Studies of the immunosupressive effects of the derivative compounds use doses �5-12 times their anti-fertility dosage� (Zhen 1995).

Individual evaluation of each of the extracts is time-consuming and expensive. Although there is no consistent testing program, various extracts have passed mutagenicity and toxicity testing. Researchers are continuing to investigate Tripterygium�s immune suppression mechanisms. One surprising result came from an study of tripchlorolide, which shows opposite effects on the immune system depending on the dose. Mice given a low dose of tripchlorolide showed enhanced immune function, while mice given a high dose showed signs of immune suppression (Lou 1990).
All studies of the various Tripterygium preparations have shown that they do not affect libido, body weight or hormones, which are some of the undesirable side effects associated with hormonal male contraception.

more at https://www.malecontraceptives.org/me...ipterygium.php
- Jim
Life is just one damned thing after another - Elbert Hubbard

Reply With Quote
Reply Bookmark and Share

arthritis, herbs, rheumatoid, thunder god vine

Thread Tools
Display Modes

Similar Threads
Thread Thread Starter Forum Replies Last Post
Rheumatoid Arthritis 'on the rise in women' kind2creatures Bones & Joints 5 08-06-2010 04:53 AM
Potassium and Rheumatoid Arthritis Harry Hirsute Bones & Joints 0 06-01-2008 10:42 PM
Cod Liver Oil May Improve Rheumatoid Arthritis Symptoms Harry Hirsute Bones & Joints 0 03-25-2008 11:38 AM
Rose Hips for Rheumatoid Arthritis Harry Hirsute Bones & Joints 0 06-21-2007 01:14 AM
Rheumatoid Arthritis and Food Allergies Harry Hirsute Bones & Joints 30 02-26-2007 01:40 PM