02-27-2008, 09:35 PM
|
 |
Lecturer
|
� |
Join Date: Apr 2006
Location: Propecia, CA
Posts: 1,851
|
|
Broccoli Sprout Extract Combats Bladder Cancer
Quote:
PHILADELPHIA – A concentrated extract of freeze dried broccoli sprouts cut development of bladder tumors in an animal model by more than half, according to a report in the March 1 issue of Cancer Research, a journal of the American Association for Cancer Research.
This finding reinforces human epidemiologic studies that have suggested that eating cruciferous vegetables like broccoli is associated with reduced risk for bladder cancer, according to the study’s senior investigator, Yuesheng Zhang, MD, PhD, professor of oncology at Roswell Park Cancer Institute. “Although this is an animal study, it provides potent evidence that eating vegetables is beneficial in bladder cancer prevention,” he said.
There is strong evidence that the protective action of cruciferous vegetables derives at least in part from isothyiocyanates (ITCs), a group of phytochemicals with well-known cancer preventive activities.“The bladder is particularly responsive to this group of natural chemicals,” Zhang said.
“In our experiments, the broccoli sprout ITCs after oral administration were selectively delivered to the bladder tissues through urinary excretion.”
Other cruciferous vegetables with ITCs include mature broccoli, cabbage, kale, collard greens and others. Broccoli sprouts have approximately 30 times more ITCs than mature broccoli, and the sprout extract used by the researchers contains approximately 600 times as much.
Although animals that had the most protection against development of bladder cancer were given high doses of the extract, Zhang said humans at increased risk for this cancer likely do not need to eat huge amounts of broccoli sprouts in order to derive protective benefits.
|
https://www.eurekalert.org/pub_releas...-eob022508.php
|
04-10-2008, 10:49 AM
|
|
Lecturer
|
� |
Join Date: Apr 2006
Location: Propecia, CA
Posts: 1,851
|
|
Quote:
Cruciferous veg again linked to bladder cancer protection
By Stephen Daniells
4/10/2008- An increased intake of cruciferous vegetables may slash the risk of bladder cancer by 36 per cent, says new research that attributes the benefits to the isothiocyanate content.
The benefits were limited to raw vegetables, report the researchers in the journal Cancer Epidemiology Biomarkers & Prevention, while no benefits were observed for the consumption of fruit and other vegetables.
"These data suggest that cruciferous vegetables, when consumed raw, may reduce the risk of bladder cancer, an effect consistent with the role of dietary isothiocyanates as chemopreventive agents against bladder cancer," wrote lead author Li Tang from Roswell Park Cancer Institute in Buffalo, New York.
Epidemiological and animal studies have shown that diets high in cruciferous vegetables result in fewer instances of certain cancers, especially lung, colon, breast and ovarian cancer, and builds on a study published last year that claimed to be the first epidemiological study linking isothiocyanates from cruciferous vegetable to a reduced risk of bladder cancer.
Bladder cancer is diagnosed in about 336,000 people every year worldwide, and it is three times more likely to affect men than women, according to the European School of Oncology.
The Roswell Park researchers collected dietary data from 275 hospital-based bladder cancer patients and 825 cancer-free people, and found that those who consumed the highest consumption of raw cruciferous vegetables was associated with a 36 per cent reduction in bladder cancer risk.
Furthermore, stronger protective effects were observed among current and heavy smokers with an intake of three or more servings of raw cruciferous vegetables per month associated with a 54 and 40 per cent reduction, respectively.
On the other hand, not benefits were observed when the researchers considered the combined raw and cooked cruciferous vegetable intake.
"Cooking can substantially reduce or destroy isothiocyanates, and could account for study inconsistencies," stated the authors.
|
https://nutraingredients-usa.com/news...s.asp?id=84558
|
| Thread Tools |
|
|
| Display Modes |
 Linear Mode
|
|
