Magnesium Intake and Risk of Type 2 Diabetes: Meta-analysis of prospective cohort studies
Emerging epidemiological evidence suggests that higher magnesium intake may reduce diabetes incidence.
We aimed to examine the association between magnesium intake and risk of type 2 diabetes by conducting a meta-analysis of prospective cohort studies.
RESEARCH DESIGN AND METHODS
We conducted a PubMed database search through January 2011 to identify prospective cohort studies of magnesium intake and risk of type 2 diabetes.
Reference lists of retrieved articles were also reviewed.
A random-effects model was used to compute the summary risk estimates.
Meta-analysis of 13 prospective cohort studies involving 536,318 participants and 24,516 cases detected a significant inverse association between magnesium intake and risk of type 2 diabetes (relative risk [RR] 0.78 [95% CI 0.73-0.84]).
This association was not substantially modified by geographic region, follow-up length, sex, or family history of type 2 diabetes.
A significant inverse association was observed in overweight (BMI ≥25 kg/m(2)) but not in normal-weight individuals (BMI <25 kg/m(2)), although test for interaction was not statistically significant (P(interaction) = 0.13).
In the dose-response analysis, the summary RR of type 2 diabetes for every 100 mg/day increment in magnesium intake was 0.86 (95% CI 0.82-0.89).
Sensitivity analyses restricted to studies with adjustment for cereal fiber intake yielded similar results.
Little evidence of publication bias was observed.
This meta-analysis provides further evidence supporting that magnesium intake is significantly inversely associated with risk of type 2 diabetes in a dose-response manner.
Bear in mind the first post in this thread was discussing a daily dose of 365 mg magnesium. My view is that should be regarded as the MINIMUM amount.
Formula to Calculate Magnesium Daily Requirement-
5 to 10 milligrams per day per kilo of ideal body weight or 2.5 to 4.5 milligrams per day per pound of ideal body weight.
Example: 70 kilos or 150 pounds= 350 mg. to 700 mg. daily.
I'd be happier if people took up to 600mg/daily spreading the amount equally through the day with each meal and before bedtime.
In that study jfh linked to previously they used Magnesium Aspartate.
If you wanted to do the same then
Now Foods, Magnesium & Potassium Aspartate, 120 Capsules
provide 300mg magnesium in 2 caps so taking one cap with each meal and one before bed would total 600mg. You may be best advised to work up to this over a few days and to reduce intake if stools become loose however you should be able to build up a tolerance that that level of intake.
I get mine from IHERB because they ship cheapest to UK Code WAB666 saves initial $5 discount You may find the same cheaper Amazon/Google depending on shipping to your destination.