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Corporate funding for herbal study

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The recent study is a striking instance of strange bedfellows. In this case, corporate profits proved to be the champion of traditional herbal wisdom. The lead researcher for the study is Stefan Gafner, PhD, a scientist employed by Tom\'s of Maine which markets natural personal care products, including toothpaste and dental floss. The company, started on a shoestring in 1970, was purchased by multinational conglomerate Colgate-Palmolive in 2006.

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Gafner and his fellow researchers analyzed licorice root to identify the compounds work against bacteria. They found that two compounds, licoricidin and licorisoflavan A, offered the strongest anti-bacterial benefits. Both substances were shown to kill two of the major bacteria that were responsible for promoting gum disease. Licoricidin was also found to kill a third bacteria responsible for gum disease. In their article, the researchers say that these two licorice substances may treat or even prevent the oral infections which lead to tooth loss.

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Establishing licorice root\'s ability to fight oral infections will help many people. Statistics from the National Institute of Dental and Craniofacial Research indicate that nearly 92% of American adults and seniors have had some form of tooth decay in 59% of teens and 42% of children aged 11. More than 80% of adults in the US may have gum disease, often without knowing it. Gum disease, which in extreme cases can result in tooth loss, is also a risk factor in many types of heart and lung disease.

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If you plan to use licorice to improve your oral hygiene, remember that natural remedies should be used with informed awareness. Herbal experts recommend that people with high blood pressure or heart disease exercise caution and not take large amounts of licorice over extended periods. Also, the herb is not recommended for pregnant women. Like most herbs, licorice root can interact with some prescription drugs, causing side-effects.

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It is good to read about a corporate conglomerate\'s profit motive put to good use for once, validating the wisdom of traditional herbal healing.

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\r\n \r\n Licorice kills viruses and bacteria, raises interferon, is a steroidal anti-inflammatory, helps other herbs to absorb and function better.
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\nIt will help the liver, kidneys and the adrenals, making it one of the top adaptogens. It also prolongs the effects of cortisol, which will slow down production by the adrenals. And as you build up the adrenals they will not over secrete the cortisol so easily.
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\nYucca root and licorice root are both steroidal anti-inflammatories and both help build up the flora.
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\nLicorice root is one of the best DHT blockers. Taking this several times a day can therefore help reduce the hair loss.
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\nLicorice root is a great substitute for the drug Prednisone as an anti-inflammatory, and it prolongs the effects of Prednisone.
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\nAdding licorice root, especially Chinese licorice root, to your supplements will benefit your health greatly. There have been reports of problems with blood pressure, but you would have to consume a very large quantity to see any such problems.\r\n
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\r\n \r\n Licorice root should not be used by people with diabetes.\r\n
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\r\n Originally Posted by dogwoman\r\n View Post\r\n
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Licorice root should not be used by people with diabetes.
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Why is that? Are you thinking licorice candy or licorice root?
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\r\n \r\n The metabolic syndrome, including type 2 diabetes, insulin resistance, obesity/abdominal obesity, hypertension and dyslipidemia, is a major public health problem. Peroxisome proliferator-activated receptor- (PPAR-) ligands such as thiazolidinediones are effective against this syndrome. In this study, we showed that nonaqueous fractions of licorice (Glycyrrhiza uralensis Fisher) extracted with ethanol, ethyl acetate and acetone, but not an aqueous extract, had PPAR- ligand-binding activity with a GAL4-PPAR- chimera assay. Some prenylflavonoids including glycycoumarin, glycyrin, dehydroglyasperin C and dehydroglyasperin D, a newly found compound, were identified as active compounds with PPAR- ligand-binding activity in the nonaqueous fraction of licorice. A licorice ethanolic extract contained these four active compounds at a total concentration of 16.7 g/100 g extract. Feeding the licorice ethanolic extract at 0.1–0.3 g/100 g diet [100 to 300 mg/(kg body · d)] for 4 wk decreased (P < 0.05) blood glucose level in younger (6 wk old) and older (13 wk old) diabetic KK-Ay mice and reduced (P < 0.05) weights of intra-abdominal adipose tissues in high fat diet–induced obese C57BL mice. An increase in blood pressure in spontaneously hypertensive rats was suppressed (P < 0.01) by 3 wk of oral administration of the licorice ethanolic extract at 300 mg/(kg body · d). These findings indicate that licorice ethanolic extract is effective in preventing and ameliorating diabetes, ameliorating abdominal obesity and preventing hypertension, and suggest that licorice ethanolic extract would be effective in preventing and/or ameliorating the metabolic syndrome.
\n Read more at: https://jn.nutrition.org/cgi/content/...ct/133/11/3369\r\n \r\n
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And also
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\r\n \r\n Glycyrrhizin
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\n Glycyrrhizin, the active ingredient in licorice, has blood sugar and cholesterol lowering properties, according to a study published in the February 2011 issue of the "Journal of Pharmacy and Pharmacology." In the study on laboratory animals, glycyrrhizin improved blood glucose levels and glucose tolerance, decreased insulin levels and lowered cholesterol and triglyceride levels. Insulin-secreting cells in the pancreas were also reduced in number. Antioxidant levels of superoxide dismutase and catalase were increased and levels of oxidized lipids were decreased by licorice extract. Iron-associated free radical formation was counteracted by licorice extract, as well, in the study.
\n Glabridin
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\n Glabridin, a phytoestrogen compound in licorice, may offer protection from oxidation and atherosclerosis in some diabetics, according to a study published in the October 2010 issue of the journal "Phytotherapy Research." Diabetic women are at higher risk for cardiovascular disease than non-diabetic women and chronic high blood sugar levels cause oxidative and inflammatory stress due to the loss of estrogen\'s protective effects. In the study, glabridin increased antioxidant enzymes by as much as 3.5 times in the high blood sugar environment of diabetes, implying a strong protective influence against the damaging effects of elevated glucose. The researchers concluded that glabridin may be a useful supplement for preventing oxidation and atherosclerosis in diabetic women.
\n Glycyrin
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\n Glycyrin, a main active compound in licorice, decreased blood sugar levels significantly in a study on laboratory animals published in the December 2003 issue of the journal "Bioorganic and Medicinal Chemistry Letters." In the study on laboratory animals, several antioxidants were identified, one of which, the the researchers noted is a new compound.
\n Roasted Versus Raw
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\n The journal "Bioscience, Biotechnology and Biochemistry" reported in its June 2007 issue on a study that found roasted licorice had better blood sugar regulating effects than raw licorice in laboratory animals. Roasted licorice consistently improved insulin secretion and increased insulin receptor sensitivity in the pancreas, leading to improved pancreatic function.
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\r\n \r\n Licorice is also good for insomnia and the adrenals.\r\n
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\r\n \r\n Licorice root can lower blood sugar, JFH. There are many contraindications for licorice root. It is contraindicated for kidney and liver disease. It is dangerous for a pregnant woman to use licorice root, and it is not recommended for lactating women. Licorice root promotes the body to produce estrogen, which is something a person with breast cancer should avoid. Anybody who wishes to use this herb should research the contraindications.\r\n
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\r\n \r\n It is dangerous for pregnant women to take many things. It is always necessary to do your own research before taking any herbs. Just because herbs are "natural", doesn\'t mean they are not powerful.
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\nLicorice contains phytoestrogen, and should be avoided in cases of estrogen dominance.
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\nBut then, you should:
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\nAvoid Coffee, Decaffeinated Coffee, and Beer.
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\nAvoid Sunflower Seeds, Red Clover Tea, Camomille Tea, Alfalfa Sprouts, Queen Anne\'s lace (wild carrot), Pomegranate, Fennel,Licorice, Red Clover, Yucca, Hops (Beer) and Motherwort.
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\nAvoid Phytoestrogens that block and interfere with the action of Natural Progesterone.
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\nAvoid Bloodroot, Ocotillo, Mandrake, Oregano, Damiana, Pennyroyal, Verbenna, Nutmeg, Tumeric, Yucca, Thyme, Calamus rt., Red Clover, Goldenseal, Licorice, Mistletoe, Cumin, Fennel, Camomille, Cloves.\r\n
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Old 01-12-2012, 06:08 PM
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Wink Licorice Root for Oral Infections and Gum Disease

Licorice Root for oral infections/gum disease...

Quote:
Corporate funding for herbal study

The recent study is a striking instance of strange bedfellows. In this case, corporate profits proved to be the champion of traditional herbal wisdom. The lead researcher for the study is Stefan Gafner, PhD, a scientist employed by Tom's of Maine which markets natural personal care products, including toothpaste and dental floss. The company, started on a shoestring in 1970, was purchased by multinational conglomerate Colgate-Palmolive in 2006.

Gafner and his fellow researchers analyzed licorice root to identify the compounds work against bacteria. They found that two compounds, licoricidin and licorisoflavan A, offered the strongest anti-bacterial benefits. Both substances were shown to kill two of the major bacteria that were responsible for promoting gum disease. Licoricidin was also found to kill a third bacteria responsible for gum disease. In their article, the researchers say that these two licorice substances may treat or even prevent the oral infections which lead to tooth loss.

Establishing licorice root's ability to fight oral infections will help many people. Statistics from the National Institute of Dental and Craniofacial Research indicate that nearly 92% of American adults and seniors have had some form of tooth decay in 59% of teens and 42% of children aged 11. More than 80% of adults in the US may have gum disease, often without knowing it. Gum disease, which in extreme cases can result in tooth loss, is also a risk factor in many types of heart and lung disease.

If you plan to use licorice to improve your oral hygiene, remember that natural remedies should be used with informed awareness. Herbal experts recommend that people with high blood pressure or heart disease exercise caution and not take large amounts of licorice over extended periods. Also, the herb is not recommended for pregnant women. Like most herbs, licorice root can interact with some prescription drugs, causing side-effects.

It is good to read about a corporate conglomerate's profit motive put to good use for once, validating the wisdom of traditional herbal healing.

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decay, gingivitis, gums, herbs, infection, licorice root, tooth

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