This information is only based on an in-vitro study, but it may help to explain some of the benefits that have been attributed to mangosteen:

"A recent in-vitro study entitled "Garcina mangostana Liquid Dietary Supplement Mango-xan: Its Anti-Inflammatory Effects" showed Mango-xan(R) Antioxidant Recovery Formula from Pure Fruit Technologies to significantly reduce cyclo-oxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX) enzymes. A considerable amount of research has established that COX-2 and 5-LOX enzymes are elevated during pain and inflammation. The study results will be presented as part of the American Chemical Society's 233rd National Meeting and Exposition being held March 25 - 29, 2007 in Chicago, IL."

https://www.npicenter.com/anm/templat...8086&zoneid=28

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