Magnesium Supplementation May Reduce Risk of Diabetes

pinballdoctor

\r\n \r\n Magnesium regulates calcium, so taking them together is not a bad idea, especially if they are both from citrate.
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\nAlso, potassium must balance with magnesium and calcium.\r\n

Ted_Hutchinson

\r\n \r\n Magnesium Intake and Risk of Type 2 Diabetes: Meta-analysis of prospective cohort studies

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\r\n \r\n Abstract
\nOBJECTIVE
\n Emerging epidemiological evidence suggests that higher magnesium intake may reduce diabetes incidence.
\nWe aimed to examine the association between magnesium intake and risk of type 2 diabetes by conducting a meta-analysis of prospective cohort studies.
\n RESEARCH DESIGN AND METHODS
\n We conducted a PubMed database search through January 2011 to identify prospective cohort studies of magnesium intake and risk of type 2 diabetes.
\n Reference lists of retrieved articles were also reviewed.
\n A random-effects model was used to compute the summary risk estimates.
\nRESULTS
\n Meta-analysis of 13 prospective cohort studies involving 536,318 participants and 24,516 cases detected a significant inverse association between magnesium intake and risk of type 2 diabetes (relative risk [RR] 0.78 [95% CI 0.73-0.84]).
\n This association was not substantially modified by geographic region, follow-up length, sex, or family history of type 2 diabetes.
\n A significant inverse association was observed in overweight (BMI ≥25 kg/m(2)) but not in normal-weight individuals (BMI <25 kg/m(2)), although test for interaction was not statistically significant (P(interaction) = 0.13).
\n In the dose-response analysis, the summary RR of type 2 diabetes for every 100 mg/day increment in magnesium intake was 0.86 (95% CI 0.82-0.89).
\n Sensitivity analyses restricted to studies with adjustment for cereal fiber intake yielded similar results.
\n Little evidence of publication bias was observed.
\nCONCLUSIONS
\n This meta-analysis provides further evidence supporting that magnesium intake is significantly inversely associated with risk of type 2 diabetes in a dose-response manner.\r\n \r\n

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Bear in mind the first post in this thread was discussing a daily dose of 365 mg magnesium. My view is that should be regarded as the MINIMUM amount.
\nFormula to Calculate Magnesium Daily Requirement-
\n5 to 10 milligrams per day per kilo of ideal body weight or 2.5 to 4.5 milligrams per day per pound of ideal body weight.
\n
\nExample: 70 kilos or 150 pounds= 350 mg. to 700 mg. daily.
\nI\'d be happier if people took up to 600mg/daily spreading the amount equally through the day with each meal and before bedtime.
\n
\nIn that study jfh linked to previously they used Magnesium Aspartate.
\nIf you wanted to do the same then
\n Now Foods, Magnesium & Potassium Aspartate, 120 Capsules provide 300mg magnesium in 2 caps so taking one cap with each meal and one before bed would total 600mg. You may be best advised to work up to this over a few days and to reduce intake if stools become loose however you should be able to build up a tolerance that that level of intake.
\n I get mine from IHERB because they ship cheapest to UK Code WAB666 saves initial $5 discount You may find the same cheaper Amazon/Google depending on shipping to your destination.\r\n

jfh · � #1 � 03-31-2011, 08:42 AM

I think you probably already know about magnesium. Reminder, try to find a magnesium supplement that is bound by something other than oxide. Don't get magnesium oxide. It tends to burn the intestinal wall, and it is not absorbed by the body very well. And remember to take magnesium supplement away from calcium. Magnesium is a powerful calcium channel blocker. It is best to take calcium in the morning. Calcium constricts the muscles, including the smooth muscles of the arteries. Magnesium is best at night. Magnesium relaxes the smooth muscles, helping blood pressure and calming you.

https://www.nhiondemand.com/hsjarticl...m_medium=email Magnesium Supplementation May Reduce Risk of Diabetes.

Diabetes mellitus is a chronic condition of insufficient insulin availability in relation to need. This can represent an absolute insulin deficiency, impaired insulin secretion, defective insulin receptors on target cells, or insulin that is inactivated before it is able to function. Diabetes mellitus is a disease in which the body does not produce or does not use insulin effectively. It is not simply hyperglycemia.
Magnesium is involved in the interaction of more than 300 enzyme reactions in the body. It is necessary for the transmission of nerve impulses, temperature regulation, detoxification, energy production and the formation of healthy bones and teeth. It is also vital for cardiovascular health.
Results from a recent study suggest that supplementation with magnesium reduces insulin resistance and lowers the risk of developing type 2 diabetes in overweight people. The double-blind, placebo-controlled, randomized trial included 52 volunteers who either received a daily dose of 365 mg magnesium or placebo for six months. The results revealed that insulin sensitivity improved significantly following magnesium supplementation. It was also found that fasting glucose levels improved by about seven percent in the magnesium group. These findings suggest that magnesium plays a significant role in improving insulin sensitivity and reducing the risk of type 2 diabetes in overweight people.1
1 Mooren FC, Kruger K, Volker K, et al. Oral magnesium supplementation reduces insulin resistance in non-diabetic subjects - a double-blind, placebo-controlled, randomized trial. Diabetes Obes Metab. 2010.

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