Wondering if you can help.. my mum has alzheimers at the age of 60. I have spent hours trying to research the best 'alternative' methods that might help her. We have started mum on low dose of coconut oil (as per Mary Newport advice) and she seems to be responding well - more engaged and positive. We are trying to up this dose. From my research on the web other things which seem to be good if you already have alzheimers are:
Turmeric
Niacinamide
Alpha Lipic Acid
Sage
Does anyone know if turmeric in capsule form would help? If so could you recommend brand?
Niacinamide - due to the study in mice on this I am going to be starting my mum on this on a low dose to start with at 250mg.
Alpha Lipic Acid - any testimonials on this?
Sage - any advice on this one?
I guess I am trying to come up with an alternative treatment plan in one. The consultant dishes out the Alzheimers drug but it won't cure. I am looking for anything alternative and would be willing to give it a go.
Many thanks
xxx
Hi lizzy1, welcome to the forum! Here's our wiki page about Alzheimer's, with some informative links at the bottom. I'm trying to take a spoonful of unrefined extra virgin coconut oil daily, just as a preventative. That seems like it's an important supplement for treatment of the disease. Happy to hear your taking good care of your mother, I wish her the best.
The two things that come to mind are increasing her circulation through exercise. Even a daily walk around the block is a start. The second thing I thought of is increasing her omega 3 fatty acids. Fish oils are a very good source.
Other things to consider are:
ginko biloba
lecithin
Alpha Lipoic Acid would be good to supplement with...https://www.ncbi.nlm.nih.gov/pubmed/18655815
PS: I learned on this forum that Alpha Lipoic Acid is a chelator of heavy metals and should be taken with something cleansing like Chlorella.
And in this thread, there are some suggesions for turmeric brands, and a positive mention of sage... /f45/20130-turmeric-alzheimers.html
I would work at increasing her coconut oil dosage as quickly as possible. There is no indicaiton that withholding would do any good nor any indication that up to 3 tablespoons as day would harm.
If you don't want to give that much coconut oil you can get medium chain triglycerides in capsule form.. she could possibly take some of each. The only downside to coconut oil that I am aware of is that it can give some people the runs.
Give the tumeric at the same time that you give the coconut oil as it facilitates absorption. she should also take bioperine with it, 5mg, again to facilitate absorption.
Otherwise it looks like you have a good protocol to me.
The only other idea I can think of, and because we have no clue what causes alzheimers, although we do understand what the physical changes are be know not what causes them I would look into MMS and consider that. MMS has helped a number of cases of "brain" disease including alzheimers. We must also consider that what causes a condiiton in one person may have a different cause in another. go to www.jimhumble.biz for further info.
One other thing you might consider is Lipsomal vitamin c with gluathione. Glutathione is the most powerful antioxidant the body can utilize. Typically it is made by the body. But lipsomal forms is the first oral application that works. go to www.letstalkhealth.com and look at their lipsomal products. I would try two months of it and see what you think.
Under no circumstances would I give my mom any alzheimers medication. They have absolutely NO proof that these drugs are of any benefit. I have watched many an alzheimers patient march into the decline and death while on them till the bitter end.
__________________
Please be advised
I advocate all health blogs linked to NMT.
Read them and explore MMS and CS.
It may be the best chance that you have to heal yourself
While you may find you want to speed through some parts of this interview it's useful if you understand how reducing refined carbohydrate is as important as increasing intake of Medium Chain Triglycerides. (MCT from Coconut oil)
Remember that Aricept (Alzheimer's drug) works by increasing the life of CHOLINE in the brain and rather than using drugs (with side effects) to prolong the life of choline it's MORE IMPORTANT to ensure your diet has good sources of choline Why you should eat more (not less) cholesterol
PS I find it difficult to understand why if God is telling her to get this message out, why she doesn't explain the basics of her program in a bit more detail online. Seems to me there is more emphasis on money making at this site than actually trying to help others prevent or treat Alzheimer's.
Seems to me the cheapest source of the supplement her husband found most helpful,
SOLGAR Phosphatidylserine, 200 mg, 60 Softgels IHERB $43.98 AMAZON 2 FOR $76.00 US shipping free.
The research daily dosage contained 300 mg PS and 37.5 mg Eicosapentaenoic acid + DHA so wasn't exactly the same as the example of similar product from IHERB (you'd need 6 capsules daily to make 300mg PS.)
Looks like you'd get more Phospholipids, omega-3 rich 420 mg and omega-3 fatty acids, total 300 mg 2 softgels daily for your money from Source Naturals, Arctic Pure, Krill Oil, 500 mg, 60 Softgels Iherb $20.44
(these aren't going to cure the underlying condition but may delay progression so will be required until life ends hence the need to get best value for money)
Bear in mind when reading the section on Vitamins they didn't review vitamin D3 the creation of which declines naturally as we age by 75 you only make 25% of that your skin made at age 25 so as you get older you naturally require MORE from supplements and the same applies to MELATONIN. except that's made in pineal gland/digestive system rather than skin.
The physiologically active form of vitamin D, 1,25-dihydroxyvitamin D(3), is a fat-soluble steroid hormone with a well established role in skeletal health.
A growing body of evidence suggests low vitamin D levels also play a role in the pathogenesis of a wide range of non-skeletal, age-associated diseases including cancer, heart disease, type 2 diabetes mellitus and stroke.
Low levels of serum 25-hydroxyvitamin D [25(OH)D], a stable marker of vitamin D status, are also associated with increased odds of prevalent cognitive dysfunction, Alzheimer's disease and all-cause dementia in a number of studies, raising the possibility that vitamin D plays a role in the aetiology of cognitive dysfunction and dementia.
To date, the majority of human studies reporting associations between vitamin D and cognition or dementia have been cross-sectional or case-control designs that do not permit us to exclude the possibility that such associations are a result of disease progression rather than being causal.
Animal and in vitro experiments have identified a number of neuroprotective mechanisms that might link vitamin D status to cognitive dysfunction and dementia, including vasoprotection and amyloid phagocytosis and clearance, but the clinical relevance of these mechanisms in humans is not currently clear.
Two recent, large, prospective studies go some way to establish the temporal relationship with cognitive decline.
The relative risk of cognitive decline was 60% higher (relative risk = 1.6, 95% CI 1.2, 2.0) in elderly Italian adults with severely deficient 25(OH)D levels (<25 nmol/L) when compared with those with sufficient levels (≥75 nmol/L).
Similarly, the odds of cognitive decline were 41% higher (odds ratio = 1.4, 95% CI 0.9, 2.2) when elderly US men in the lowest quartile (≤49.7 nmol/L) were compared with those in the highest quartile (≥74.4 nmol/L).
To our knowledge, no prospective studies have examined the association between 25(OH)D levels and incident dementia or neuroimaging abnormalities.
The possible therapeutic benefits of vitamin D have attracted considerable interest as over 1 billion people worldwide are thought to have insufficient 25(OH)D levels and these levels can be increased using inexpensive and well tolerated dietary supplements.
Bear in mind for UK readers with a current average 25(OH)D level 30nmol/l 12ng/ml will require in the region of 5000iu/daily D3 to safely into the highest quartile and stay there.
I have cognitive problems with my ME/CFS and I would research if they are also good for Alzheimers but I've improved with:
Phosphatidylserine (Neuro PS)
Bio PQQ
Standard Process Neurotrophin PMG
Grape Seed Extract
Acetyl-L-carinitine
NAC
Alpha Lipoic Acid
TMG
I also detoxed metals and other toxins and took a lot of vitamins and minerals including D and B, took tons of antioxidants and have done things to try and increase glutathione, took a lot of good oils and a good diet with sufficient protein and lots of vegetables and fruits so I don't know to what extent these also helped.
Just wanted to say many thanks for the replies I have received so far on this topic, I am very grateful. I need to go through and digest all the information however this is really positive getting this advice/ideas and tips in one place.......
Abstract
In the present study, we tested the efficacy and safety of Huperzine A in treatment of mild to moderate vascular dementia (VaD).
This was a randomized, double-blinded, placebo-controlled study with 78 patients with mild to moderate VaD.
The participants were randomized to receive either vitamin C (100-mg bid) as placebo (n = 39) or Huperzine A (0.1-mg bid) (n = 39) for 12 consecutive weeks.
The mini-mental state examination (MMSE), clinical dementia rating (CDR), and activities of daily living (ADL) scores were used for the assessment of cognition.
The assessments were made prior to treatment, and 4, 8, and 12 weeks of the treatment.
The adverse effects of the treatment were also recorded.
After 12 weeks of treatment, the MMSE, CDR, and ADL scores significantly improved in the Huperzine A group (P < 0.01 for all comparisons), whereas the placebo group did not show any such improvement (P > 0.05 for all comparisons).
No serious adverse events were recorded during the treatment. Conclusion:
Huperzine A can significantly improve the cognitive function in patients with mild to moderate vascular dementia.
Further, the medicament is safe.
Although this study used 100mg/d Huperzine A the paper I link to in post #9 of this thread talks about studies finding much higher amounts were required.
So as this is a safe medication it may be worth going for a higher amount such as
Source Naturals, Huperzine A, 200 mcg, 120 Tablets IHERB price $21.27
Turmeric capsules, 3 a day plus a couple turmeric extract capsules.
I think Curcumin (turmeric) is extremely useful partly because it also binds with the Vitamin D receptor so tends to support the actions of vitamin D3.
It may be a good idea to use a form such as
Doctor's Best, Meriva, Phytosome Curcumins, 500 mg, 60 Veggie Caps IHERB price: $14.99 as this is carried in Phospholipids so is supporting the earlier suggestions to increase PhosphatidylSerine which is part of the phosphorlipid family.
Quote:
Also, Vitamin D 5000 IU daily for a couple weeks
As the need for vitamin d increases with age 5000iu daily should continue ad infinitum or until a 25(OH)D test shows levels are above 60ng/ml or 150nmol/l in which case it may be reduced to maintain a 25(OH)d level around the 60ng/ml mark.
Quote:
and UP the coconut oil
Sure But incorporate it in foods or drinks so it is a part of the meal rather than as a supplement.
1) in our experimental conditions we did not observe any anti-amyloidogenic and fibril-destibilizing effect played by resveratrol, as proposed by other groups
2) resveratrol exerts its neuroprotective activity not only against Aβ but also against Aβ-metal complexes;
3) resveratrol acts as a ROS scavenger against those generated by Aβ-Fe, Aβ-Cu and Aβ-Zn, thereby reducing their toxicity;
4) eventually, resveratrol is not sufficient to fully block Aβ-Al and Aβ-Cu toxicity.
So if money is no object it looks like resveratrol MAY help.
Biotivia, Transmax, Trans-Resveratrol, 500 mg, 60 Capsules but it's IHERB price $72.00 (discount for quantity) Much cheaper AMAZON
Alzheimers - an alternative treatment plan?
Here's our wiki page about Alzheimer's, with some informative links at the bottom. I'm trying to take a spoonful of unrefined extra virgin coconut oil daily, just as a preventative. That seems like it's an important supplement for treatment of the disease. Happy to hear your taking good care of your mother, I wish her the best.
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