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Old 04-19-2008, 01:25 PM
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Default Beta Glucans - Oral vs Injectable & More

β-glucans have been extensively studied for their
pharmacological effects. Despite in-depth research, little is
known about the optimal dose and/or optimal route of application.

In this paper, we are reporting the result of comparing
the immunostimulating activities of four commercially
available glucans differing both in their solubility and
source. In addition, we compared intraperitoneal and oral
application, and the differences between a single versus
repeated doses.

Our data showed strong differences in activities of individual
glucans, with glucan yeast-derived #300 being the
best, and grain-derived ImmuneFiber being the worst.

Furthermore, we demonstrated that oral delivery of glucan
resulted in significant immunological activity, which albeit
slightly lower, corresponded with injectable application.
Depending on the applied dose, the effects of individual
glucans were long-lasting and in some cases, lasted up to
two weeks.

In conclusion, our report represents further evidence
about differences among commercial glucans and shows
that these biological response modifiers can be similarly
active when used in both injectable and oral form.
https://www.ana-jana.org/jana_journal.cfm (issue: JANA Volume 11, No. 1, 2008)
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