11-12-2007, 11:01 AM
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Join Date: Apr 2006
Location: Propecia, CA
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Prebiotics May Decrease Inflammation in Elderly
Quote:
In a prospective, randomized, double-blind, controlled study involving 74 elderly subjects (mean age: 84 years) at risk of malnutrition or already undernourished, results indicate that oral nutritional supplementation with prebiotics may improve certain inflammatory parameters.
The subjects received daily liquid supplements with oligosaccharides (1.3 g/250 ml) or without oligosaccharides, for a period of 12 weeks.
At intervention end, significant decreases in TNF-alpha mRNA and IL-6 mRNA levels were observed in the prebiotics-supplemented group. Additionally, a decrease in serum levels of sCD14 - a product shed by activated macrophages - was observed in the prebiotics-supplemented group.
Thus, the results of this study suggest that in elderly subjects at risk of malnutrition receiving oral nutritional supplementation, the addition of prebiotics may exert a beneficial effect on systemic pro-inflammatory markers.
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https://www.vitasearch.com/get-clp-summary/36836
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