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Old 02-10-2009, 05:31 PM
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Default Blood Medicine - Part 3

Rivers of Life and Death
Part 3

Magnesium and Hemoglobin, Blood Coagulation, Aluminum and Zeta Potential

�The transport of oxygen in blood is undertaken by hemoglobin, the largest component of red blood cells. This protein collects oxygen in respiratory organs, mainly in the lungs, and releases it in tissues in order to generate the energy necessary for cell survival. Hemoglobin is one of the most refined proteins because its evolution and small mutations in its structure can produce anemia and other severe pathologies,� publishes the Institute for Research in Biomedicine (IRB Barcelona).

They continue, �More than a hundred years of study have led to the knowledge that hemoglobin uses mechanisms of cooperativity to optimize its function; that is to say, to collect the greatest amount of oxygen possible in the lungs and release it in tissues. These mechanisms of cooperativity are related to changes in the structure of the hemoglobin protein.The structure of hemoglobin is easily compromised by heavy metals like mercury (as are all sulfur bearing proteins like insulin etc) and no one really wants anyone to shout this out from the tops of the mountains. Thus the vast majority of doctors and dentists continue to walk in the darkness created by ignorance of basic medical science. (In my upcoming book New Paradigms in Diabetic Medicine we nail down the mercury sulfur bond death destruction pact using insulin as a model.)

On the other hand there are substances that optimize the structure of hemoglobin and other complex proteins. Magnesium enhances the binding of oxygen to haem proteins.(1) The concentration of Mg2+ in red cells is relatively high but free Mg2+ is much lower in oxygenated red blood cells then in deoxygenated ones. In nature the oxygen is generated by the chemical sunshine that is chlorophyll, and carried in the human body by the haemoglobin in the blood to be used by cells to produce energy in the form of ATP. Both chlorophyll and hemoglobin are connected with porphyrin compounds in that iron/Fe porphyrins form the haem of hemoglobin while chlorophyll, the photosynthetic pigment of plants is a magnesium/Mg2+-containing porphyrin.

Mg2+ is needed as a co-factor in the generation of ATP; some 90% of intracellular Mg2+ may be associated with ATP or ADP and associated enzymes. The transfer of ATP phosphate is assisted by a complex formed by the binding of magnesium to phosphate groups in ATP (Gropper et al, 2005, p.399; Shils, 1994). Fe3+ is the oxygenated form of iron in haemoglobin (Shriver and Atkins, 1999, p.650); the Mg2+ of chlorophyll and ATP generated by the mitochondria helps to stabilize this which is what keeps the blood red and reflects alkalinity (Truchot, 1975). This process occurs in the heart region according to TCM theory which is associated with the colour red. Thus there is a transition from the green of chlorophyll to the red of the blood.

Na(+),K(+)-ATPase is a transmembrane protein that transports sodium and potassium ions across cell membranes during an activity cycle that uses the energy released by ATP hydrolysis. Mercury, nickel, aluminum, and other toxic metals are documented to inhibit Na(+),K(+) -ATPase function at very low levels of exposure.2,3 Studies have found that in asthma, lupus, rheumatoid arthritis, Scleroderma, celiac/chron�s/IBS, and eczema cases there was a reduction in serum magnesium and red blood cell(RBC) membrane Na(+)-K+ ATPase activity and an elevation in plasma serum digoxin.4,5

Magnesium and zinc prevent the binding of carbon monoxide/CO to haem which otherwise binds 25,000 times more strongly than does oxygen. The dissociation of oxygen is also helped by magnesium, because it provides an oxygen adsorption isotherm which is hyperbolic. It also ensures that the oxygen dissociation curves are sigmoidal which maximizes oxygen saturation with the gaseous pressure of oxygen (Murray et al pp. 65-67).

Oxygen dissociation with increased delivery to the tissues is increased by magnesium through elevation of 2,3-bisphosphoglycerate/DPG (Darley, 1979) Magnesium stabilizes the ability of the phorphyrin ring to fluoresce in cooperation with phosphorus which is a sink for the light energy generated during photosynthesis. Free-radical attack of haemoglobin yields ferryl haemoglobin [HbFe4+] (D�Agnillo and Alayash, 2001), which is inhibited by magnesium (Rock et al, 1995).

Both chlorophyll and blood have a pH of about 7.4. 7.5 is the physiological pH of the plant which is usually within 0.2 pH units of the optimum for photosynthesis (Dodd and Bidwell, 1971); in chlorophyll respiration, carbonic acid is removed from the water increasing the pH and carbonic acid is also involved in the mechanism by which respiration increases blood pH. Furthermore - Porphyrins are cyclic compounds with four pyrrole rings linked through methenyl bridges [-HC=]. Metal ions such as iron or magnesium are bound to the nitrogen atom of the pyrrole rings.

Blood Coagulation

The processes of inflammation and coagulation are
intimately linked. Multiple inflammatory mediators that
are released to fight infection also promote coagulation.

Severe sepsis results from the body's systemic over-response to infection. This over-response disrupts homeostasis through an uncontrolled cascade of inflammation, coagulation, and impaired fibrinolysis. Allopathic medicine hides a lot of information about pathology with its rigid diagnostic system. What we see in severe sepsis is a dramatic overreaction but there are shades of pathology like there are shades of color.

Zeta is but one of the factors affecting blood flow and coagulation - the other is an immune hypersensitivity response, of which there are many types. The propensity for blood to clot too rapidly is an important prognosticator for the development of, progression of, and recovery from a number of serious pathological conditions whose pathogeneses either arise directly from or are modulated by the blood clotting process. These diseases include heart attack, stroke, coronary artery disease, deep vein thrombosis, and pulmonary embolism, among others. Of these diseases, coronary artery disease is the leading cause of mortality in the United States

Aluminum and Zeta Potential

Since 1934, aluminum hydroxide has been used as an
adjuvant to boost the immune response from vaccines.

To increase your zeta potential you must avoid aluminum. Aluminum is used in water treatment plants to cause materials to settle out of solution. It does this by reducing the zeta potential. In your body aluminum does the same thing, causing coagulation of your blood, and deposits and plaques in your arteries, brain and throughout your body. Aluminum is found in municipally treated water, cooking utensils, vaccinations, non-clumping salt and baking powder just to name a few things.

The hepatitis B vaccine (Energix-B) is given at birth, 2 and six months of age. Each dose contains 250 micrograms (mcg) of aluminum. The DTaP shot (Infanrix) is given at 2, 4, 6 and 15 months. Each dose contains 625mcg of aluminum. The Hib vaccine (Pedvax) is given at 2, 4, and 12 months. Each dose contains 125mcg of aluminum. The hepatitis A vaccine (Havrix) is given at 12 and 18 months. Each dose contains 250mcg of aluminum. Thus, babies who follow the CDC immunization schedule are injected with nearly 5000mcg (5mg) of aluminum by 18 months of age.
Over 7000 reference articles on aluminum toxicity exist in various data bases, all recognizing the toxicity. Despite the number of references to aluminum toxicity, the FDA has always exempted it from testing by putting it on their Generally Regarded as Safe (GRAS) list. Aluminum can be added to foods, medicines or water without restriction from the FDA.

The first head of the FDA quit over aluminum being added to the GRAS List with no testing required and no limits to the amount that can be added to food or medicine.

Thus aluminum is broadly used in food and medicines. It is in buffered aspirin, antacids, antiperspirant, in prenatal feeding solutions, vaccinations which are stabilized with aluminum with their associated bacterial infections, toothpaste, baby wipes, vaginal douches, and aluminum cans to name a few. In any chemical combination such as drugs, may be positive or negative depending on the net valance of all the elements in the formula.

Aluminum has three (3) positive ions, so a single ion of aluminum will reduce surface charge, reduce carrying capacity and increase surface tension by 64x more than an ion of Sodium, which has one positive charge. - Thomas M. Riddick

Aluminum is just harmful to life. Aluminum is a protoplasmic poison and a deadly, persistent neurotoxin. Aluminum is a known toxin that can cause encephalitis, bone disease and anemia in susceptible people. Though aluminum is less toxic than mercury, arsenic, lead or cadmium, it is a persistent poison that increases the toxicity of other heavy metals. Dr. Shaw found in animal studies that aluminum hydroxide shows statistically significant increases in anxiety (38 percent); memory deficits (41 times the errors as in the sample group); and an allergic skin reaction (20 percent). Tissue samples after the mice were �sacrificed� showed neurological cells were dying. Inside the mice�s brains, in a part that controls movement, 35 percent of the cells were destroying themselves.

A heavy metal has a density at least 5 times that of water and cannot be metabolized by the body, therefore accumulating in the body. Heavy metal toxicity can cause our mental functions, energy, nervous system, kidneys, lungs and other organ functions to decline.

According to Dr. Russell Blaylock, �Removal of thimerosal, even if complete, will not solve the problem of autism. It will help tremendously, but will not stop the epidemic of autism. Speaking of her autistic patients, Dr Stephanie Cave said, �You would be amazed at the devastation in their chemistries when you get down to the cellular level.� She also said, �I think in later years we are going to look back at aluminum the way we are looking at mercury now.� (6)

Autopsy reports on Alzheimer's patients found 70% more aluminum in the brain.

�Aluminum salts are used as vaccine adjuvants based on their ability to improve dendritic cell response to presented antigens. The aluminum concentration of vaccines varies from 0.125 to 0.85 mg/dose, which would produce concentrations of approximately 0.7 to 4.5 uM, if uniformly distributed in the body water of a seven kg infant,� reported Dr. M. Waly at Northeastern University, who found that at these low concentrations cellular problems are created independently and in combination with mercury.7

Aluminum in infant feeding solutions has been shown to reduce the mental development index creating permanent learning problems in children.

Dr. Boyd Haley �The presence of aluminum dramatically increased the rate of neuronal death caused by thimerosal. Therefore, the aluminum and thimerosal combination found in vaccines produces a toxic mixture that cannot be compared to situations where thimerosal alone was the toxic exposure.� (8)

Mercury and aluminum not only are directly toxic to brain cells but also over stimulate the brain�s immune system. - Dr. Russel Blaylock

Symptoms and Diseases of Aluminum: Flatulence, headaches, dry skin, weak and aching muscles, senility, spleen pain, stomach pain, liver dysfunction, kidney dysfunction, neuromuscular disorders, osteomalacia, colitis, anemia, Alzheimer�s disease, amyotrophic lateral sclerosis, hemolysis, leukocytosis, porphyria, heartburn, memory loss, numbness, paralysis, Parkinson's disease, excessive perspiration, leg twitching, cavities, colds, behavioral problems, constipation

The kidneys eliminate Aluminum from the body and so people with renal problems are at risk of Aluminum toxicity. All infants have reduced renal function and may not be able to effectively excrete excessive Aluminum. Kidney function is low at birth and reaches adult level by 1-2 years of age. The presence of Aluminum in a vaccine can cause small nodules to develop under the skin of some babies. These nodules are usually transient in nature and disappear spontaneously after a few weeks. In rare cases extreme hypersensitivity to Aluminum results in persistent nodules.

Mark Sircus Ac., OMD
Director International Medical Veritas Association
Winning The War On Cancer

Dr. Mark Sircus is the Director of Natural Allopathic Studies of the faculty of the DaVinci College of Holistic Medicine, an international school specializing in Holistic Medicine. Professor Sircus is also the director of oriental medical studies. A member of the International Association for Distance Learning, The DaVinci College of Holistic Medicine is accredited by the Complementary Medicine Association in the United Kingdom.


1 Terwilliger and Brown, 1993; Takenhiko and Weber; Wood and Dalgleish, 1973

2 Hisatome I, Kurata Y, et al; Block of sodium channels by divalent mercury: role of specific cysteinyl residues in the P-loop region. Biophys J. 2000;79(3):1336-45

3 Effect of Chronic Exposure to Aluminum on Isoform Expression and Activity of Rat (Na+/K+)ATPase Virg�lia S. Silva, Ana I. Duarte, A. Cristina Rego, Catarina R. Oliveira and Paula P. Gon�alves Toxicological Sciences 2005 88(2):485-494

4 Overzet K, Gensler TJ, et al; Small nucleolar RNP Scleroderma autoantigens associate with phosphorylated serine/arginine splicing factors during apoptosis. Arthritis Rheum 2000 Jun;43(6):1327:36

5 Feighery L, Collins C, Feighery C, Mahmud N, Coughlan G, Willoughby R, Jackson J. Anti-transglutaminase antibodies and the serological diagnosis of coeliac disease. Br J Biomed Sci. 2003;60(1):14-8

6 Cave, Stephanie, Mitchell, Deborah "What Your Doctor May Not Tell You About Children's Vaccinations", Warner Books, 01 September, 2001.
7 Waly, M. et al Activation of methionine synthase by insulin-like growth factor-1 and dopamine: a target for neurodevelopmental toxins and thimerosal. Department of Pharmaceutical Sciences, Northeastern University. Molecular Psychiatry (2004) 1-13

8 Haley, Boyd. Mercury and Thimerosal Toxicity: A Factor in Autism

Legal Notice: The Author specifically invokes the First Amendment rights of freedom of speech and of the press without prejudice. The information written is published for informational purposes only under the rights guaranteed by the First Amendment of the Constitution for the United States of America, and should not in any way be used as a substitute for the advice of a physician or other licensed health care practitioner. The statements contained herein have not been evaluated by the FDA. The products discussed herein are not intended to diagnose, cure, prevent or treat any disease. Images, text and logic are copyright protected. ALL rights are explicitly reserved without prejudice, and no part of this essay may be reproduced except by written consent. �2008 by Mark Sircus
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