Quote:
Originally Posted by will dc
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will dc,
Excellent choice, will dc! You already may have read one of the articles I'm going to recommend.
Anyone considering supplementing with high doses of niacin should be aware of the possible side effects. In general, your liver acts as a clearing house/detoxifier for the body, and as such is subjected to various degrees of stress as it deals with any and all medications you may be taking (including over-the counter medications), nutritional supplements including herbal supplements (some of unknown origin/purity; the news media occasionally reports incidents of contamination with lead and/or other heavy metals), alcoholic beverages, etc. The combined effect of several of those can be damaging as well, even if there is no contamination if the liver is subjected to a high degree of stress from disease, alcohol, medication, etc.
To better familiarize yourself with the potential side effects of high dose nicacin (including what constitutes a high dose, recommended dose, etc.) I suggest you read the two articles at the following Links. Each is well researched and well written by competent professionals, and together they provide an excellent introduction to the subject at hand.
When you bring up the first article (from the
University of Maryland MEDICAL CENTER), to save yourself some time I suggest you first read the first seven brief paragraphs down to "
Cholesterol" under the section entitled, "
Overview:". Note in particular the difference between
niacin (nicotinic acid) and
niacinamide (nicotinamide). Then scroll down and read the paragraph entitled, "
Precautions", and the paragraph entitled, "
Possible Interactions" Then scroll back up and read the rest of the article for recommended dosages, etc.
https://www.umm.edu/altmed/articles/v...-b3-000335.htm
For this second article (from the
Linus Pauling Institute at
Oregon State University), I'm providing the Link which will take you directly to the paragraph entitled, "
Safety". Again, to save yourself some time I suggest you read it first and then scroll back up to read the remainder of the article for recommended dosages, etc., as it's a little lengthy but well worth reading in its entirety. Note at the bottom of the page the authors and the reviewer and their credentials:
https://lpi.oregonstate.edu/infocente.../niacin#safety
Then after having armed yourself with that information, you'll be better prepared to do the following as you will know exactly what to look for and you will more easily understand what you're reading. If you would like additional information, put the following into your SEARCH box and read some of the hits -
niacin AND liver damage. Then for still more information, remove the
AND and do the same -
niacin liver damage. That will provide some different hits, although there will be some repetition.